Early nasogastric enteral nutrition for severe acute pancreatitis: a systematic review.

Early nasogastric enteral nutrition for severe acute pancreatitis: a systematic review. Research Abstract Details 

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Early nasogastric enteral nutrition for severe acute pancreatitis: a systematic review. Abstract Text:

Kun Jiang,Xin-Zu Chen,Qing Xia,Wen-Fu Tang,Lei Wang,

AIM: To evaluate the effectiveness and safety of early nasogastric enteral nutrition (NGEN) for patients with severe acute pancreatitis (SAP). METHODS: We searched Cochrane Central Register of Controlled Trials (Issue 2, 2006), Pub-Medline (1966-2006), and references from relevant articles. We included randomized controlled trials (RCTs) only, which reported the mortality of SAP patients at least. Two reviewers assessed the quality of each trial and collected data independently. The Cochrane Collaboration's RevMan 4.2.9 software was used for statistical analysis. RESULTS: Three RCTs were included, involving 131 patients. The baselines of each trial were comparable. Meta-analysis showed no significant differences in mortality rate of SAP patients between nasogastric and conventional routes (RR = 0.76, 95% CI = 0.37 and 1.55, P = 0.45), and in other outcomes, including time of hospital stay (weighted mean difference = -5.87, 95% CI = -20.58 and 8.84, P = 0.43), complication rate of infection (RR = 1.41, 95% CI = 0.62 and 3.23, P = 0.41) or multiple organ deficiency syndrome (RR = 0.97, 95% CI = 0.27 and 3.47, P = 0.97), rate of admission to ICU (RR = 1.00, 95% CI = 0.48 and 2.09, P = 0.99) or conversion to surgery (RR = 0.66, 95% CI = 0.12 and 3.69, P = 0.64), as well as recurrence of re-feeding pain and adverse events associated with nutrition. CONCLUSION: Early NGEN is a breakthrough in the management of SAP. Based on current studies, early NGEN appears effective and safe. Since the available evidence is poor in quantity, it is hard to make an accurate evaluation of the role of early NGEN in SAP. Before recommendation to clinical practice, further high qualified, large scale, randomized controlled trials are needed.

Early nasogastric enteral nutrition for severe acute pancreatitis: a systematic review. Publishing Authors By Initials

K Jiang,XZ Chen,Q Xia,WF Tang,L Wang,

For similar diagnosis: prognosis: treatment outcome research abstracts see: diagnosis: prognosis: treatment outcome research

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Early nasogastric enteral nutrition for severe acute pancreatitis: a systematic review. Journal Published:

PUBLICATION TYPE: Review

Journal: World journal of gastroenterology : WJG

VOLUME: 13

Page Numbers: 5253-60

Journal Abbreviation: World J. Gastroenterol.

ISSN: 1007-9327

DAY: 21

MONTH: Oct

YEAR: 2007

Early nasogastric enteral nutrition for severe acute pancreatitis: a systematic review. Information

Number of References: 32

LANGUAGE: eng

NlmUniqueID: 100883448

Early nasogastric enteral nutrition for severe acute pancreatitis: a systematic review. Keywords Mesh Terms:

KEYWORDS: Treatment Outcome

MESH TERMS: therapy

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Grant and Affiliation Information for Early nasogastric enteral nutrition for severe acute pancreatitis: a systematic review.

AFFILIATION: Department of Integrated Traditional Chinese and Western Medicine, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.

Country: China

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MEDLINETA: World J Gastroenterol

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