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Early findings in a pilot study of anterior cervical interbody fusion in which recombinant human bone morphogenetic protein-2 was used with poly(L-lactide-co-D,L-lactide) bioabsorbable implants.

Early findings in a pilot study of anterior cervical interbody fusion in which recombinant human bone morphogenetic protein-2 was used with poly(L-lactide-co-D,L-lactide) bioabsorbable implants. Research Abstract Details 

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  • Early findings in a pilot study of anterior cervical interbody fusion in which recombinant human bone morphogenetic protein-2 was used with poly(L-lactide-co-D,L-lactide) bioabsorbable implants. Abstract Text:

    todd h lanmanTodd H Lanman,thomas j hopkinsThomas J Hopkins,

    OBJECT: The goal of this study was to assess the efficacy of bioabsorbable interbody spacers in cervical spine fusion. METHODS: The authors report on a prospective examination of 20 patients with degenerative cervical disc disease who underwent anterior cervical fusion at 28 total levels. The authors used Infuse bone graft (that is, recombinant human bone morphogenetic protein-2 applied to an absorbable collagen sponge and contained within a Cornerstone-HSR bioabsorbable spacer. Multiple-level fusions were performed in 30% of these patients. At 3 months postfusion, radiographs and computerized tomography scans demonstrated bridging bone in 100% of the patients. Improvement from baseline scores in physical functioning, mental health, and bodily pain was demonstrated at 3 months postoperatively according to results of the Short Form-36 Version 2 health survey. There were no device-related complications. CONCLUSIONS: The results in this series indicate that the use of Cornerstone-HSR as a bioabsorbable interbody spacer in combination with Infuse bone graft may be an alternative treatment for cervical spine fusion.

    Early findings in a pilot study of anterior cervical interbody fusion in which recombinant human bone morphogenetic protein-2 was used with poly(L-lactide-co-D,L-lactide) bioabsorbable implants. Publishing Authors By Initials

    th lanmanTH Lanman,tj hopkinsTJ Hopkins,

    For similar peptides: intercellular signaling peptides and proteins: cytokines: transforming growth factor beta research abstracts see: peptides: intercellular signaling peptides and proteins: cytokines: transforming growth factor beta research

    PUBMED ID PMID:

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    Early findings in a pilot study of anterior cervical interbody fusion in which recombinant human bone morphogenetic protein-2 was used with poly(L-lactide-co-D,L-lactide) bioabsorbable implants. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Neurosurgical focus

    VOLUME: 16

    Page Numbers: E6

    Journal Abbreviation:

    ISSN: 1092-0684

    DAY: 15

    MONTH: 03

    YEAR: 2004

    Early findings in a pilot study of anterior cervical interbody fusion in which recombinant human bone morphogenetic protein-2 was used with poly(L-lactide-co-D,L-lactide) bioabsorbable implants. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 100896471

    Early findings in a pilot study of anterior cervical interbody fusion in which recombinant human bone morphogenetic protein-2 was used with poly(L-lactide-co-D,L-lactide) bioabsorbable implants. Keywords Mesh Terms:

    KEYWORDS: Transforming Growth Factor beta

    MESH TERMS: methods

    Chemical & Substance for Abstract: Early findings in a pilot study of anterior cervical interbody fusion in which recombinant human bone morphogenetic protein-2 was used with poly(L-lactide-co-D,L-lactide) bioabsorbable implants. Information

    Substance Name: poly(lactide)

    Registry Number: 26969-66-4

    Grant and Affiliation Information for Early findings in a pilot study of anterior cervical interbody fusion in which recombinant human bone morphogenetic protein-2 was used with poly(L-lactide-co-D,L-lactide) bioabsorbable implants.

    AFFILIATION: California Spine Group, Century City Hospital, Los Angeles, California, USA.

    Country: United States

    United States Research PublicationUnited States Research Publication

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    ACRONYM:

    MEDLINETA: Neurosurg Focus

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    Early findings in a pilot study of anterior cervical interbody fusion in which recombinant human bone morphogenetic protein-2 was used with polyL-lactide-co-D,L-lactide bioabsorbable implants Related Publications

     

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