Dysphagia severity and aspiration following postoperative radiation for locally advanced oropharyngeal cancer.

Dysphagia severity and aspiration following postoperative radiation for locally advanced oropharyngeal cancer. Research Abstract Details 

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Dysphagia severity and aspiration following postoperative radiation for locally advanced oropharyngeal cancer. Abstract Text:

Nam P Nguyen,Cheryl Frank,Candace C Moltz,Paul Vos,Carrie Millard,Herbert J Smith,Suresh Dutta,Howard Lee,Tomas Martinez,Ulf Karlsson,Ly M Nguyen,Sabah Sallah,

The aim of the present study was to assess dysphagia severity following postoperative radiation for locally advanced oropharyngeal cancer. PATIENTS AND METHODS: Eighteen patients with oropharyngeal carcinoma had undergone postoperative radiation. There were eight base of tongue, eight tonsils, and two soft palate carcinomas. All the patients had undergone modified barium swallow (MBS) to assess the persistence of dysphagia (more than one month) post-treatment. All the patients were cancer-free at the time of the swallowing study. Dysphagia severity was graded as 1-7. RESULTS: At a median follow-up of 12 months, there were three grade 2, four grade 3, two grade 4, five grade 5, two grade 6, and two grade 7. Only three patients (17%) had normal swallow post-treatment. Six patients (33%) had mild to moderate dysphagia (grade 3-4). Nine patients (50%) developed aspiration (grade 5-7). Among the patients who developed aspiration, four (22%) required tube feeding for severe aspiration. CONCLUSION: Long-term (more than one year) dysphagia following postoperative radiation for oropharyngeal cancer may be symptomatic of permanent damage to the swallowing mechanism. Evaluation of patients who complain of persistence of dysphagia a year or more following treatment should include MBS, because of the increased risk of aspiration.

Dysphagia severity and aspiration following postoperative radiation for locally advanced oropharyngeal cancer. Publishing Authors By Initials

NP Nguyen,C Frank,CC Moltz,P Vos,C Millard,HJ Smith,S Dutta,H Lee,T Martinez,U Karlsson,LM Nguyen,S Sallah,

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Dysphagia severity and aspiration following postoperative radiation for locally advanced oropharyngeal cancer. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Anticancer research

VOLUME: 28

Page Numbers: 431-4

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ISSN: 0250-7005

DAY: 3

MONTH: 04

YEAR: 2008

Dysphagia severity and aspiration following postoperative radiation for locally advanced oropharyngeal cancer. Information

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LANGUAGE: eng

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AFFILIATION: Department Radiation Oncology, University of Arizona, 1501 N. Campbell Ave, Tucson, AZ 85724-5081, USA. NamPhong.Nguyen@yahoo.com

Country: Greece

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MEDLINETA: Anticancer Res

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