Dynamics of prion disease transmission in mule deer.

Dynamics of prion disease transmission in mule deer. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Dynamics of prion disease transmission in mule deer. Abstract Text:

Michael W Miller,N Thompson Hobbs,Simon J Tavener,

Chronic wasting disease (CWD), a contagious prion disease of the deer family, has the potential to severely harm deer populations and disrupt ecosystems where deer occur in abundance. Consequently, understanding the dynamics of this emerging infectious disease, and particularly the dynamics of its transmission, has emerged as an important challenge for contemporary ecologists and wildlife managers. Although CWD is contagious among deer, the relative importance of pathways for its transmission remains unclear. We developed seven competing models, and then used data from two CWD outbreaks in captive mule deer and model selection to compare them. We found that models portraying indirect transmission through the environment had 3.8 times more support in the data than models representing transmission by direct contact between infected and susceptible deer. Model-averaged estimates of the basic reproductive number (R0) were 1.3 or greater, indicating likely local persistence of CWD in natural populations under conditions resembling those we studied. Our findings demonstrate the apparent importance of indirect, environmental transmission in CWD and the challenges this presents for controlling the disease.

Dynamics of prion disease transmission in mule deer. Publishing Authors By Initials

MW Miller,NT Hobbs,SJ Tavener,

For similar prion diseases: wasting disease, chronic research abstracts see: prion diseases: wasting disease, chronic research

PUBMED ID PMID:

MEDLINE DATE:

Dynamics of prion disease transmission in mule deer. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Ecological applications : a publication of the Eco

VOLUME: 16

Page Numbers: 2208-14

Journal Abbreviation:

ISSN: 1051-0761

DAY: 3

MONTH: Dec

YEAR: 2006

Dynamics of prion disease transmission in mule deer. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9889808

Dynamics of prion disease transmission in mule deer. Keywords Mesh Terms:

KEYWORDS: Wasting Disease, Chronic

MESH TERMS: transmission

Chemical & Substance for Abstract: Dynamics of prion disease transmission in mule deer. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Dynamics of prion disease transmission in mule deer.

AFFILIATION: Colorado Division of Wildlife, Wildlife Research Center, 317 West Prospect Road, Fort Collins 80526, USA. mike.miller@state.co.us

Country: United States

AGENCY: United States NIDCR

GRANT: DEB-0091961

ACRONYM: DE

MEDLINETA: Ecol Appl

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Dynamics of prion disease transmission in mule deer Related Publications

• A versatile automatic gas-sampling system.
• Dynamics of prion disease transmission in mule deer.