Dynamic oxygen-enhanced MRI versus quantitative CT: pulmonary functional loss assessment and clinical stage classification of smoking-related COPD.

Dynamic oxygen-enhanced MRI versus quantitative CT: pulmonary functional loss assessment and clinical stage classification of smoking-related COPD. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Dynamic oxygen-enhanced MRI versus quantitative CT: pulmonary functional loss assessment and clinical stage classification of smoking-related COPD. Abstract Text:

Yoshiharu Ohno,Hisanobu Koyama,Munenobu Nogami,Daisuke Takenaka,Sumiaki Matsumoto,Makoto Obara,Kazuro Sugimura,Yoshiharu Ohno,Hisanobu Koyama,Munenobu Nogami,Daisuke Takenaka,Sumiaki Matsumoto,Makoto Obara,Kazuro Sugimura,Yoshiharu Ohno,Hisanobu Koyama,Munenobu Nogami,Daisuke Takenaka,Sumiaki Matsumoto,Makoto Obara,Kazuro Sugimura,

OBJECTIVE: The purpose of the present study is to prospectively compare the capability of dynamic oxygen-enhanced MRI and quantitative CT for pulmonary functional loss assessment and clinical stage classification of smoking-related chronic obstructive pulmonary disease (COPD). SUBJECTS AND METHODS: Ten nonsmoking and 61 consecutive smoking-related COPD subjects underwent dynamic oxygen-enhanced MRI, CT, and pulmonary function tests. COPD subjects were classified into four clinical stages on the basis of the ATS-ERS guidelines. Wash-in time and relative enhancement ratio maps were generated by pixel-by-pixel analyses. Mean wash-in time and relative enhancement ratio were determined as averages of region of interest (ROI) measurements. CT-based functional lung volumes were measured on quantitative CT using the density-masked CT technique. For comparison of assessment capability for smoking-related functional loss, the three parameters were correlated with the percentage predicted forced expiratory volume in 1 second (%FEV1) and the percentage predicted diffusing capacity of the lung for carbon monoxide corrected for alveolar volume (%DL(CO)/VA). To determine the clinical stage classification capability, these parameters were statistically compared for nonsmoking subjects and all clinical stages of smoking-related COPD subjects. RESULTS: Correlation between mean wash-in time and %FEV1 (r = -0.74, p < 0.0001) and between mean relative enhancement ratio and %DL(CO)/VA (r = 0.66, p < 0.0001) was better than that between CT-based functional lung volume and either %FEV1 (r = 0.61, p < 0.0001) or %DL(CO)/VA (r = 0.56, p < 0.0001). Mean wash-in time showed a significant difference between nonsmoking and smoking-related COPD subjects at all clinical stages (p < 0.05). CONCLUSION: Dynamic oxygen-enhanced MRI has potential for pulmonary functional loss assessment and clinical stage classification of smoking-related COPD as does quantitative CT.

Dynamic oxygen-enhanced MRI versus quantitative CT: pulmonary functional loss assessment and clinical stage classification of smoking-related COPD. Publishing Authors By Initials

Y Ohno,H Koyama,M Nogami,D Takenaka,S Matsumoto,M Obara,K Sugimura,Y Ohno,H Koyama,M Nogami,D Takenaka,S Matsumoto,M Obara,K Sugimura,Y Ohno,H Koyama,M Nogami,D Takenaka,S Matsumoto,M Obara,K Sugimura,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Dynamic oxygen-enhanced MRI versus quantitative CT: pulmonary functional loss assessment and clinical stage classification of smoking-related COPD. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: AJR. American journal of roentgenology

VOLUME: 190

Page Numbers: W93-9

Journal Abbreviation:

ISSN: 1546-3141

DAY: 23

MONTH: Feb

YEAR: 2008

Dynamic oxygen-enhanced MRI versus quantitative CT: pulmonary functional loss assessment and clinical stage classification of smoking-related COPD. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7708173

Dynamic oxygen-enhanced MRI versus quantitative CT: pulmonary functional loss assessment and clinical stage classification of smoking-related COPD. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Dynamic oxygen-enhanced MRI versus quantitative CT: pulmonary functional loss assessment and clinical stage classification of smoking-related COPD. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Dynamic oxygen-enhanced MRI versus quantitative CT: pulmonary functional loss assessment and clinical stage classification of smoking-related COPD.

AFFILIATION: Department of Radiology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, Hyogo 650-0017, Japan.

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: AJR Am J Roentgenol

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Dynamic oxygen-enhanced MRI versus quantitative CT: pulmonary functional loss assessment and clinical stage classification of smoking-related COPD Related Publications

• Assessment of health-related quality of life after radiofrequency ablation or laparoscopic surgery for small renal cell carcinoma: a prospective study with medical outcomes Study 36-Item Health Survey (SF-36).
• Binding of ADP-ribose polymer with histone.
• Bisphenol A induces permanent squamous change in mouse prostatic epithelium.
• Cell wall sheath surrounding calcium oxalate crystals in mulberry idioblasts.
• Combination of CT during arterial portography and double-phase CT hepatic arteriography with multi-detector row helical CT for evaluation of hypervascular hepatocellular carcinoma.
• Crystallization of rat liver aldolase.
• Hemoproteins in microsomes in liver of tumor-bearing rats.
• Human Fc epsilon RIalpha-specific human single-chain Fv (scFv) antibody with antagonistic activity toward IgE/Fc epsilon RIalpha-binding.
• Identification and characterization of a novel germ line p53 mutation in familial gastric cancer in the Japanese population.
• Immunochemical properties of the specific anti-4-azoquinoline 1-oxide antibody.
• Influence of detector collimation and beam pitch for identification and image quality of ground-glass attenuation and nodules on 16- and 64-detector row CT systems: Experimental study using chest phantom.
• Influence of inversion pulse type in assessing lung-oxygen-enhancement by centrically-reordered non-slice-selective inversion-recovery half-Fourier single-shot turbo spin-echo (HASTE) sequence.
• Influences of prolonged apnea and oxygen inhalation on pulmonary hemodynamics during breath holding: Quantitative assessment by velocity-encoded MR imaging with SENSE technique.
• Kinetic studies on the liver catalase depression in vivo using 3,5-dicarbethoxy-1,4-dihydrocollidine.
• Magnetic resonance imaging findings of endometrioid adenocarcinoma of the ovary.
• Magnetic resonance screening trial for hepatic metastasis in patients with locally controlled choroidal melanoma.
• Myeloperoxidases of human myeloid leukemia cells HL-60 grown in culture and in nude mice.
• Naftopidil, a selective alpha-1 adrenoceptor antagonist, inhibits growth of human prostate cancer cells by G1 cell cycle arrest.
• Normal uptake of 18F-FDG in the testis: an assessment by PET/CT.
• Paclitaxel Carboplatin chemotherapy as a second-line chemotherapy for advanced platinum resistant urothelial cancer in Japanese cases.
• Peptide mimics of monocyte chemoattractant protein-1 (MCP-1) with an antagonistic activity.
• Percutaneous radiofrequency ablation with transarterial embolization is useful for treatment of stage 1 renal cell carcinoma with surgical risk: results at 2-year mean follow up.
• Proceedings: Anti-poly(ADP-ribose) antibody and its specificity.
• Proceedings: Effect of poly(ADP-ribose) on DNases of the nuclei of rat liver and ascites hepatoma cells.
• Recombinant human bone morphogenetic protein-2 promotes osteogenesis within atelopeptide type I collagen solution by combination with rat cultured marrow cells.
• STIR turbo SE MR imaging vs. coregistered FDG-PET/CT: quantitative and qualitative assessment of N-stage in non-small-cell lung cancer patients.
• Studies on algal cytochromes VI: some properties and amino acid sequence of cytochrome c6 from a green alga, Bryopsis maxima.
• Unsuspected bone and soft tissue lesions identified at cancer screening using positron emission tomography.
• [A case of primary testicular malignant lymphoma associated with contralateral testicural recurrence after a seven-year interval]
• alphaPIX nucleotide exchange factor is activated by interaction with phosphatidylinositol 3-kinase.