[Drug treatment of cholestatic liver diseases]

[Drug treatment of cholestatic liver diseases] Research Abstract Details 

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[Drug treatment of cholestatic liver diseases] Abstract Text:

J Reichen,

After a brief summary of the pathophysiology and natural history of different cholestatic disorders novel forms of treatment are considered. Treatment of different syndromes with ursodeoxycholic acid is considered in some depth. While the substance has clearly proven its efficacy in the symptomatic treatment, its influence on hard parameters such as survival and transplantation requirements remains to be documented. S-adenoylmethionine has shown to be efficaceous in some but not all studies on pruritus of pregnancy. The substance holds promise in other cholestatic disorders as well, but clearly more studies are needed before its therapeutic potential can be appreciated. Finally, nowadays orthotopic liver transplantation should be considered early in patients with progressive cholestatic liver disorders.

[Drug treatment of cholestatic liver diseases] Publishing Authors By Initials

J Reichen,

For similar polycyclic compounds: steroids: bile acids and salts: cholic acids: deoxycholic acid: ursodeoxycholic acid research abstracts see: polycyclic compounds: steroids: bile acids and salts: cholic acids: deoxycholic acid: ursodeoxycholic acid research

PUBMED ID PMID:

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[Drug treatment of cholestatic liver diseases] Journal Published:

PUBLICATION TYPE: Review

Journal: Therapeutische Umschau. Revue thérapeutique

VOLUME: 49

Page Numbers: 315-25

Journal Abbreviation:

ISSN: 0040-5930

DAY: 12

MONTH: May

YEAR: 1992

[Drug treatment of cholestatic liver diseases] Information

Number of References: 9

LANGUAGE: ger

NlmUniqueID: 407224

[Drug treatment of cholestatic liver diseases] Keywords Mesh Terms:

KEYWORDS: Ursodeoxycholic Acid

MESH TERMS: administration & dosage

Chemical & Substance for Abstract: [Drug treatment of cholestatic liver diseases] Information

Substance Name: Colchicine

Registry Number: 64-86-8

Grant and Affiliation Information for [Drug treatment of cholestatic liver diseases]

AFFILIATION: Institut für Klinische Pharmakologie, Universität Bern.

Country: SWITZERLAND

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MEDLINETA: Ther Umsch

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