Drug related problems with Antiparkinsonian agents: consumer Internet reports versus published data.

Drug related problems with Antiparkinsonian agents: consumer Internet reports versus published data. Research Abstract Details 

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Drug related problems with Antiparkinsonian agents: consumer Internet reports versus published data. Abstract Text:

Sabrina ,York Francis ,Marion Schaefer,Sabrina ,York Francis ,Marion Schaefer,

PURPOSE: There is currently a lack of detailed information concerning drug related problems in the outpatient treatment of Parkinson's disease. METHODS: Problems associated with drug treatment communicated anonymously in Parkinson's disease online forums were therefore retrospectively searched and documented for 1 year. RESULTS: Based on postings concerning 12 drugs for the treatment of Parkinson's disease, a total of 238 drug related problems were identified and categorised using the Problem Intervention Documentation (PI-Doc). Of these, 153 were adverse drug reactions. Adverse drug reactions associated with the skin were relatively common, but central effects such as cognitive or psychiatric changes, effects on the sleep/waking system and other problems like headache and dizziness accounted for the highest percentage of adverse events. A comparison with data from scientific literature revealed a number of differences. This means that an analysis of online forums detected a number of drug related problems that were otherwise largely invisible. These were mainly associated with the qualitative aspects of treatment such as medication handling, dosage and individual problems concerning adverse events. In addition, the described method of identifying and classifying drug related problems in Internet forums may also be seen as a contribution to the international discussion about consumer reports and pharmacovigilance. The information about adverse drug reactions given by Internet users can be seen as a valuable adjunct to clinical trial data and as being very timely with regard to the event itself. CONCLUSION: Online forums may be considered as a suitable source of observational information to complement data from randomised clinical trials.

Drug related problems with Antiparkinsonian agents: consumer Internet reports versus published data. Publishing Authors By Initials

S ,YF ,M Schaefer,S ,YF ,M Schaefer,

For similar investigative techniques: epidemiologic methods: epidemiologic study characteristics as topic: epidemiologic studies: case-control studies: retrospective studies research abstracts see: investigative techniques: epidemiologic methods: epidemiologic study characteristics as topic: epidemiologic studies: case-control studies: retrospective studies research

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Drug related problems with Antiparkinsonian agents: consumer Internet reports versus published data. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Pharmacoepidemiology and drug safety

VOLUME: 16

Page Numbers: 1161-6

Journal Abbreviation:

ISSN: 1053-8569

DAY: 29

MONTH: Oct

YEAR: 2007

Drug related problems with Antiparkinsonian agents: consumer Internet reports versus published data. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9208369

Drug related problems with Antiparkinsonian agents: consumer Internet reports versus published data. Keywords Mesh Terms:

KEYWORDS: Retrospective Studies

MESH TERMS: adverse effects

Chemical & Substance for Abstract: Drug related problems with Antiparkinsonian agents: consumer Internet reports versus published data. Information

Substance Name: Antiparkinson Agents

Registry Number: 0

Grant and Affiliation Information for Drug related problems with Antiparkinsonian agents: consumer Internet reports versus published data.

AFFILIATION: Institute of Clinical Pharmacology, Charité University Medicine, CCM, Berlin, Germany. sabrina.schroeder@charite.de

Country: England

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MEDLINETA: Pharmacoepidemiol Drug Saf

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