Drug induced nightmares--an etiology based review.

Drug induced nightmares--an etiology based review. Research Abstract Details 

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Drug induced nightmares--an etiology based review. Abstract Text:

OBJECTIVE: Recent clinical trials have included patient complaints of nightmares as a category of reportable medication side effects. This study integrates that data into current experimental and theoretical research of drug effects that may alter dreaming and nightmares. The objective is to provide a clinical and theoretical framework useful in categorizing the potential and reported drug effects on nightmares. METHODOLOGY: This study reviews case reports and clinical trials that have reported nightmares or alterations in dreaming occurring secondary to medication usage. These data are analysed as to the probability of the drug/nightmare association, and integrated into current electrophysiological and neurochemical theories of dreaming and nightmares. RESULTS: Pharmacological agents affecting the neurotransmitters norepinephrine, serotonin and dopamine are clearly associated with patient reports of nightmares. Agents affecting immunological response to infectious disease are likely to induce nightmares in some patients. A possible association exists between reports of nightmares and agents affecting the neurotransmitters acetylcholine, GABA and histamine, as well as for some anesthetics, antipsychotics and antiepileptic agents. CONCLUSION: By utilizing our current experimental and theoretical knowledge base, the potential etiology of a majority of reported drug effects on nightmares can be classified. These data support current neurochemical theories of dreaming, as well as suggesting that the biochemical basis for dreaming and nightmare induction may be more complex than generally suggested.

Drug induced nightmares--an etiology based review. Publishing Authors By Initials

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Drug induced nightmares--an etiology based review. Journal Published:

PUBLICATION TYPE: Review

Journal: Human psychopharmacology

VOLUME: 18

Page Numbers: 59-67

Journal Abbreviation: Hum Psychopharmacol

ISSN: 0885-6222

DAY: 6

MONTH: Jan

YEAR: 2003

Drug induced nightmares--an etiology based review. Information

Number of References: 59

LANGUAGE: eng

NlmUniqueID: 8702539

Drug induced nightmares--an etiology based review. Keywords Mesh Terms:

KEYWORDS: Pharmaceutical Preparations

MESH TERMS: adverse effects

Chemical & Substance for Abstract: Drug induced nightmares--an etiology based review. Information

Substance Name: Pharmaceutical Preparations

Registry Number: 0

Grant and Affiliation Information for Drug induced nightmares--an etiology based review.

AFFILIATION: Parkview Neurological Institute, University of Colorado Medical School, 1619 North Greenwood, Pueblo, Colorado 81003, USA. pueo34@juno.com

Country: England

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MEDLINETA: Hum Psychopharmacol

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