Doppler optical coherence microscopy for studies of cochlear mechanics.

Doppler optical coherence microscopy for studies of cochlear mechanics. Research Abstract Details 

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Doppler optical coherence microscopy for studies of cochlear mechanics. Abstract Text:

Stanley S Hong,Dennis M Freeman,

The possibility of measuring subnanometer motions with micron scale spatial resolution in the intact mammalian cochlea using Doppler optical coherence microscopy (DOCM) is demonstrated. A novel DOCM system is described that uses two acousto-optic modulators to generate a stable 500-kHz heterodyne frequency. Images and motion measurements are obtained using phase-resolved analysis of the interference signal. The DOCM system permits imaging with micron-scale resolution and 85-dB sensitivity and motion measurements with 100-kHz bandwidth, directional discrimination, and 30-pm/Hz(0.5) noise floor. Images and motion measurements are presented that demonstrate the ability to resolve motions of structures of interest in a mammalian cochlea in vitro including the basilar membrane, reticular lamina, tectorial membrane, and outer hair cells.

Doppler optical coherence microscopy for studies of cochlear mechanics. Publishing Authors By Initials

SS Hong,DM Freeman,

For similar diagnosis: diagnostic techniques and procedures: diagnostic imaging: ultrasonography: ultrasonography, doppler research abstracts see: diagnosis: diagnostic techniques and procedures: diagnostic imaging: ultrasonography: ultrasonography, doppler research

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Doppler optical coherence microscopy for studies of cochlear mechanics. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Journal of biomedical optics

VOLUME: 11

Page Numbers: 054014

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ISSN: 1083-3668

DAY: 3

MONTH: 12

YEAR: 2007

Doppler optical coherence microscopy for studies of cochlear mechanics. Information

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LANGUAGE: eng

NlmUniqueID: 9605853

Doppler optical coherence microscopy for studies of cochlear mechanics. Keywords Mesh Terms:

KEYWORDS: Ultrasonography, Doppler

MESH TERMS: methods

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Grant and Affiliation Information for Doppler optical coherence microscopy for studies of cochlear mechanics.

AFFILIATION: Massachusetts Institute of Technology, Research Laboratory of Electronics, Department of Electrical Engineering and Computer Science, Cambridge, Massachusetts 02139, USA.

Country: United States

AGENCY: United States NIDCD

GRANT: 1-R21-DC007111-01

ACRONYM: DC

MEDLINETA: J Biomed Opt

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