Does porcine reproductive and respiratory syndrome virus potentiate classical swine fever virus infection in weaner pigs?

Does porcine reproductive and respiratory syndrome virus potentiate classical swine fever virus infection in weaner pigs? Research Abstract Details 

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Does porcine reproductive and respiratory syndrome virus potentiate classical swine fever virus infection in weaner pigs? Abstract Text:

K R Depner,E Lange,S Pontrakulpipat,D Fichtner,

Fifteen 6-week-old crossbred weaners weighing about 12 kg each were randomly divided into three groups of five animals each. One group of pigs was inoculated first with porcine reproductive and respiratory syndrome (PRRS) virus and then 3 days later with CSF virus. The second group received classical swine fever (CSF) virus, while the third group was inoculated with PRRS virus only. The aim of the experiment was to determine whether a primary PRRS virus infection influences the clinical outcome of experimentally induced CSF in young pigs. The PRRS virus infected weaners developed mild respiratory symptoms and recovered completely. All five weaners which were inoculated with CSF virus only showed severe clinical signs typical of the acute form of CSF. One pig had to be killed 15 days post-inoculation (p.i.); the remaining four died between the 18th and 22nd day p.i. The clinical course of the animals inoculated with both viruses was slightly different from that of the pigs that received only CSF virus. Four out of five pigs from the PRRS/CSF group became febrile and viraemic earlier than the animals which received CSF virus only. These pigs had to be killed 15-17 days post CSF virus inoculation. One animal in this group survived the acute phase of CSF and recovered completely. It was concluded that the observed divergences of the clinical courses would not have been noticed under field conditions. Therefore these findings cast doubt on the relevance of PRRS virus infection potentiating significantly the clinical outcome of CSF in young pigs.

Does porcine reproductive and respiratory syndrome virus potentiate classical swine fever virus infection in weaner pigs? Publishing Authors By Initials

KR Depner,E Lange,S Pontrakulpipat,D Fichtner,

For similar biochemical phenomena, metabolism, and nutrition: nutrition physiology: child nutrition physiology: infant nutrition physiology: weaning research abstracts see: biochemical phenomena, metabolism, and nutrition: nutrition physiology: child nutrition physiology: infant nutrition physiology: weaning research

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Does porcine reproductive and respiratory syndrome virus potentiate classical swine fever virus infection in weaner pigs? Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Zentralblatt für Veterinärmedizin. Reihe B. Journa

VOLUME: 46

Page Numbers: 485-91

Journal Abbreviation: Zentralblatt Veterinarmedizin

ISSN: 0514-7166

DAY: 13

MONTH: Sep

YEAR: 1999

Does porcine reproductive and respiratory syndrome virus potentiate classical swine fever virus infection in weaner pigs? Information

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LANGUAGE: eng

NlmUniqueID: 331325

Does porcine reproductive and respiratory syndrome virus potentiate classical swine fever virus infection in weaner pigs? Keywords Mesh Terms:

KEYWORDS: Weaning

MESH TERMS: veterinary

Chemical & Substance for Abstract: Does porcine reproductive and respiratory syndrome virus potentiate classical swine fever virus infection in weaner pigs? Information

Substance Name: Antibodies, Viral

Registry Number: 0

Grant and Affiliation Information for Does porcine reproductive and respiratory syndrome virus potentiate classical swine fever virus infection in weaner pigs?

AFFILIATION: National Swine Fever Laboratory, Federal Research Center for Viral Diseases of Animals, Insel Riems, Germany. klaus.robert.depner@rie.bfav.de

Country: GERMANY

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MEDLINETA: Zentralbl Veterinarmed B

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