Does aspiration of saliva trigger nocturnal asthma?

Does aspiration of saliva trigger nocturnal asthma? Research Abstract Details 

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Does aspiration of saliva trigger nocturnal asthma? Abstract Text:

A Javaid,A P Sykes,J G Ayres,

Five adult asthmatics with nocturnal symptoms (mean FEV1 2.31 1; 2 mean PD20 histamine 1.5 unmoles), 5 asthmatics with no nocturnal symptoms (mean FEV1 l 2.97 l; mean PD20 Histamine 3.7 unmoles) and 5 non-asthmatic control subjects (mean FEV1 3.63 l; mean PD20 histamine 78 unmoles) were challenged with nebulised solutions of their own saliva or isotonic saline in a double blind crossover study to investigate whether the inhalation of saliva during sleep could cause nocturnal asthma. The maximum % fall in FEV1 with saliva was -26.6, -6.5 and -4.1 for the nocturnal, non-nocturnal and control groups respectively. The corresponding values for the maximum % fall in FEV1 with saline was -12.4, -5.5 and -3.6. The difference in maximum % fall in FEV1 with both saliva and saline was significant (p < 0.01) for the nocturnal asthmatics when compared to the non-nocturnal asthmatics. These results lend support to the hypothesis that nocturnal symptoms in asthmatic patients may be triggered by inhalation of saliva during sleep.

Does aspiration of saliva trigger nocturnal asthma? Publishing Authors By Initials

A Javaid,AP Sykes,JG Ayres,

For similar nervous system diseases: sleep disorders research abstracts see: nervous system diseases: sleep disorders research

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Does aspiration of saliva trigger nocturnal asthma? Journal Published:

PUBLICATION TYPE: Journal Article

Journal: JPMA. The Journal of the Pakistan Medical Associat

VOLUME: 44

Page Numbers: 60-2

Journal Abbreviation:

ISSN: 0030-9982

DAY: 12

MONTH: Mar

YEAR: 1994

Does aspiration of saliva trigger nocturnal asthma? Information

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LANGUAGE: eng

NlmUniqueID: 7501162

Does aspiration of saliva trigger nocturnal asthma? Keywords Mesh Terms:

KEYWORDS: Sleep Disorders

MESH TERMS: physiopathology

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Grant and Affiliation Information for Does aspiration of saliva trigger nocturnal asthma?

AFFILIATION: Chest Research Institute, Birmingham Heartlands Hospital.

Country: PAKISTAN

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MEDLINETA: J Pak Med Assoc

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