Docosahexaenoic and arachidonic acid concentrations in human breast milk worldwide.

Docosahexaenoic and arachidonic acid concentrations in human breast milk worldwide. Research Abstract Details 

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Docosahexaenoic and arachidonic acid concentrations in human breast milk worldwide. Abstract Text:

J Thomas Brenna,Behzad Varamini,Robert G Jensen,Deborah A Diersen-Schade,Julia A Boettcher,Linda M Arterburn,J Thomas Brenna,Behzad Varamini,Robert G Jensen,Deborah A Diersen-Schade,Julia A Boettcher,Linda M Arterburn,

Concentrations of the long-chain polyunsaturated fatty acids (LCPUFAs) docosahexaenoic acid (DHA, 22:6n-3) and arachidonic acid (AA, 20:4n-6) in human breast milk are important indicators of infant formula DHA and AA concentrations, and recent evidence suggests that neural maturation of breastfed infants is linked to breast-milk LCPUFA concentrations. We report a descriptive meta-analysis that considered 106 studies of human breast milk culled to include only studies that used modern analysis methods capable of making accurate estimates of fatty acid (FA) profiles and criteria related to the completeness of reporting. The final analysis included 65 studies of 2474 women. The mean (+/-SD) concentration of DHA in breast milk (by wt) is 0.32 +/- 0.22% (range: 0.06-1.4%) and that of AA is 0.47 +/- 0.13% (range: 0.24-1.0%), which indicates that the DHA concentration in breast milk is lower than and more variable than that of AA. The highest DHA concentrations were primarily in coastal populations and were associated with marine food consumption. The correlation between breast-milk DHA and AA concentrations was significant but low (r = 0.25, P = 0.02), which indicates that the mean ratio of DHA to AA in regional breast milk varies widely. This comprehensive analysis of breast-milk DHA and AA indicates a broad range of these nutrients worldwide and serves as a guide for infant feeding.

Docosahexaenoic and arachidonic acid concentrations in human breast milk worldwide. Publishing Authors By Initials

JT Brenna,B Varamini,RG Jensen,DA Diersen-Schade,JA Boettcher,LM Arterburn,JT Brenna,B Varamini,RG Jensen,DA Diersen-Schade,JA Boettcher,LM Arterburn,

For similar fluids and secretions: bodily secretions: milk, human research abstracts see: fluids and secretions: bodily secretions: milk, human research

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Docosahexaenoic and arachidonic acid concentrations in human breast milk worldwide. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: The American journal of clinical nutrition

VOLUME: 85

Page Numbers: 1457-64

Journal Abbreviation: Am. J. Clin. Nutr.

ISSN: 0002-9165

DAY: 3

MONTH: Jun

YEAR: 2007

Docosahexaenoic and arachidonic acid concentrations in human breast milk worldwide. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 376027

Docosahexaenoic and arachidonic acid concentrations in human breast milk worldwide. Keywords Mesh Terms:

KEYWORDS: Milk, Human

MESH TERMS: chemistry

Chemical & Substance for Abstract: Docosahexaenoic and arachidonic acid concentrations in human breast milk worldwide. Information

Substance Name: Arachidonic Acid

Registry Number: 506-32-1

Grant and Affiliation Information for Docosahexaenoic and arachidonic acid concentrations in human breast milk worldwide.

AFFILIATION: Division of Nutritional Sciences, Cornell University, Ithaca, NY 14850, USA. jtb4@cornell.edu

Country: United States

AGENCY: United States NIDDK

GRANT: DK07158

ACRONYM: DK

MEDLINETA: Am J Clin Nutr

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