DNA stretch during electrophoresis due to a step change in mobility.

DNA stretch during electrophoresis due to a step change in mobility. Research Abstract Details 

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DNA stretch during electrophoresis due to a step change in mobility. Abstract Text:

Patrick T Underhill,Patrick S Doyle,Patrick T Underhill,Patrick S Doyle,

We investigate DNA stretching during electrophoresis when the mobility abruptly changes. This is a simplified geometry that produces a nonhomogeneous strain rate over the scale of a single molecule. An effective Weissenberg number (Wi) and Deborah number were identified, and the degree of stretching was examined as a function of these two parameters. The system does not undergo a coil-stretch transition. The finite extensibility of the chains only affects the response if the chain is stretched to a significant fraction of the contour length. The wormlike chain shows a characteristic approach to full extension of Wi(-1/2).

DNA stretch during electrophoresis due to a step change in mobility. Publishing Authors By Initials

PT Underhill,PS Doyle,PT Underhill,PS Doyle,

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DNA stretch during electrophoresis due to a step change in mobility. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Physical review. E, Statistical, nonlinear, and so

VOLUME: 76

Page Numbers: 011805

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ISSN: 1539-3755

DAY: 19

MONTH: 07

YEAR: 2007

DNA stretch during electrophoresis due to a step change in mobility. Information

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LANGUAGE: eng

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AFFILIATION: Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

Country: United States

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MEDLINETA: Phys Rev E Stat Nonlin Soft Ma

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