Dithiane additions to vinyl epoxides: steric control over the SN2 and SN2' manifolds.

Dithiane additions to vinyl epoxides: steric control over the SN2 and SN2' manifolds. Research Abstract Details 

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Dithiane additions to vinyl epoxides: steric control over the SN2 and SN2' manifolds. Abstract Text:

Amos B Smith,Suresh M Pitram,Matthew J Gaunt,Sergey A Kozmin,

High chemoselectivity can be achieved in the addition of lithium dithiane anions to vinyl epoxides exploiting the steric nature of the dithiane substituent. Unencumbered dithiane anions afford SN2 adducts, whereas sterically encumbered anions lead primarily to SN2' adducts. Furthermore, the SN2' addition occurs syn to the vinyl epoxide.

Dithiane additions to vinyl epoxides: steric control over the SN2 and SN2' manifolds. Publishing Authors By Initials

AB Smith,SM Pitram,MJ Gaunt,SA Kozmin,

For similar organic chemicals: hydrocarbons: hydrocarbons, acyclic: alkenes: vinyl compounds research abstracts see: organic chemicals: hydrocarbons: hydrocarbons, acyclic: alkenes: vinyl compounds research

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Dithiane additions to vinyl epoxides: steric control over the SN2 and SN2' manifolds. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Journal of the American Chemical Society

VOLUME: 124

Page Numbers: 14516-7

Journal Abbreviation: J. Am. Chem. Soc.

ISSN: 0002-7863

DAY: 11

MONTH: Dec

YEAR: 2002

Dithiane additions to vinyl epoxides: steric control over the SN2 and SN2' manifolds. Information

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LANGUAGE: eng

NlmUniqueID: 7503056

Dithiane additions to vinyl epoxides: steric control over the SN2 and SN2' manifolds. Keywords Mesh Terms:

KEYWORDS: Vinyl Compounds

MESH TERMS: chemistry

Chemical & Substance for Abstract: Dithiane additions to vinyl epoxides: steric control over the SN2 and SN2' manifolds. Information

Substance Name: Lithium

Registry Number: 7439-93-2

Grant and Affiliation Information for Dithiane additions to vinyl epoxides: steric control over the SN2 and SN2' manifolds.

AFFILIATION: Department of Chemistry, Monell Chemical Senses Center and Laboratory for Research on the Structure of Matter, University of Pennsylvania, Philadelphia Pennsylvania 19104, USA. smithab@sas.upenn.edu

Country: United States

AGENCY: United States NCI

GRANT: CA-19033

ACRONYM: CA

MEDLINETA: J Am Chem Soc

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