Distribution of epithelial membrane antigen in benign and malignant lesions of the salivary glands.

Distribution of epithelial membrane antigen in benign and malignant lesions of the salivary glands. Research Abstract Details 

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Distribution of epithelial membrane antigen in benign and malignant lesions of the salivary glands. Abstract Text:

B A Gusterson,R B Lucas,M G Ormerod,

An antiserum against epithelial membrane antigen has been used to stain a variety of lesions arising in the salivary glands. In normal major and minor glands staining was localised to the ductal systems. There was no evidence of myoepithelial cell staining. The mucous elements of the submandibular and sublingual glands were negative, but in the mucous elements of the minor glands there was focal cytoplasmic positivity. There was no cytoplasmic staining of serous elements in major or minor salivary glands. In pleomorphic adenomas the luminal membrane of ductal elements was strongly positive, with focal cytoplasmic positivity in some myxoid areas. In mucoepidermoid tumours both adjacent cell membranes and cytoplasm were strongly positive. The ductal structure of adenoid cystic carcinomas were clearly delineated while the pseudoducts produced by enclosed areas of stroma were negative. All mesenchymally derived tumours were negative and a tumour previously considered as a chondroma was strongly positive. The results are discussed in relation to phenotypic heterogeneity and the histogenesis of salivary gland tumours.

Distribution of epithelial membrane antigen in benign and malignant lesions of the salivary glands. Publishing Authors By Initials

BA Gusterson,RB Lucas,MG Ormerod,

For similar salivary glands: submandibular gland research abstracts see: salivary glands: submandibular gland research

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Distribution of epithelial membrane antigen in benign and malignant lesions of the salivary glands. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Virchows Archiv. A, Pathological anatomy and histo

VOLUME: 397

Page Numbers: 227-33

Journal Abbreviation:

ISSN: 0340-1227

DAY: 20

MONTH: 02

YEAR: 1982

Distribution of epithelial membrane antigen in benign and malignant lesions of the salivary glands. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7505137

Distribution of epithelial membrane antigen in benign and malignant lesions of the salivary glands. Keywords Mesh Terms:

KEYWORDS: Submandibular Gland

MESH TERMS: immunology

Chemical & Substance for Abstract: Distribution of epithelial membrane antigen in benign and malignant lesions of the salivary glands. Information

Substance Name: Antigens

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Country: GERMANY, WEST

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MEDLINETA: Virchows Arch A Pathol Anat Hi

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