Distinct patterns of hippocampal formation activity associated with different spatial tasks: a Fos imaging study in rats.

Distinct patterns of hippocampal formation activity associated with different spatial tasks: a Fos imaging study in rats. Research Abstract Details 

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Distinct patterns of hippocampal formation activity associated with different spatial tasks: a Fos imaging study in rats. Abstract Text:

Trisha A Jenkins,Eman Amin,Gordon T Harold,John M Pearce,John P Aggleton,

Fos levels were measured in rats trained in one of two qualitatively different spatial memory tasks in a water maze. In one task, ( landmark condition) rats found a submerged platform that was always 25 cm south of a visible landmark, the absolute position of the platform and landmark changing after every trial. In the other task ( place condition), rats swam to a platform that remained in the same absolute position on every session, but changed session to session, with this task relying on the memory of allocentric cues. Despite matched swim times, the landmark condition resulted in higher levels of Fos in a wide range of cortical and subcortical sites, including the hippocampus and its connections. Structural equation modelling revealed two different patterns of hippocampal function. In the allocentric place task there was a significant association between Fos activity in the entorhinal cortices and the hippocampus proper, while in the non-allocentric landmark task this relationship was not present, but was replaced by a connection from the entorhinal cortices to the subiculum. Thus, the two different tasks engage two different modes of hippocampal activity as demonstrated by Fos expression.

Distinct patterns of hippocampal formation activity associated with different spatial tasks: a Fos imaging study in rats. Publishing Authors By Initials

TA Jenkins,E Amin,GT Harold,JM Pearce,JP Aggleton,

For similar nervous system: central nervous system: brain: prosencephalon: diencephalon: thalamus: thalamic nuclei research abstracts see: nervous system: central nervous system: brain: prosencephalon: diencephalon: thalamus: thalamic nuclei research

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Distinct patterns of hippocampal formation activity associated with different spatial tasks: a Fos imaging study in rats. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Experimental brain research. Experimentelle Hirnfo

VOLUME: 151

Page Numbers: 514-23

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ISSN: 0014-4819

DAY: 27

MONTH: 06

YEAR: 2003

Distinct patterns of hippocampal formation activity associated with different spatial tasks: a Fos imaging study in rats. Information

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LANGUAGE: eng

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Distinct patterns of hippocampal formation activity associated with different spatial tasks: a Fos imaging study in rats. Keywords Mesh Terms:

KEYWORDS: Thalamic Nuclei

MESH TERMS: physiology

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Grant and Affiliation Information for Distinct patterns of hippocampal formation activity associated with different spatial tasks: a Fos imaging study in rats.

AFFILIATION: School of Psychology, Tower Building, Cardiff University, Park Place, CF10 3YG, Cardiff, UK.

Country: Germany

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MEDLINETA: Exp Brain Res

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