Dissociable intrinsic connectivity networks for salience processing and executive control.

Dissociable intrinsic connectivity networks for salience processing and executive control. Research Abstract Details 

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Dissociable intrinsic connectivity networks for salience processing and executive control. Abstract Text:

William W Seeley,Vinod Menon,Alan F Schatzberg,Jennifer Keller,Gary H Glover,Heather Kenna,Allan L Reiss,Michael D Greicius,

Variations in neural circuitry, inherited or acquired, may underlie important individual differences in thought, feeling, and action patterns. Here, we used task-free connectivity analyses to isolate and characterize two distinct networks typically coactivated during functional MRI tasks. We identified a "salience network," anchored by dorsal anterior cingulate (dACC) and orbital frontoinsular cortices with robust connectivity to subcortical and limbic structures, and an "executive-control network" that links dorsolateral frontal and parietal neocortices. These intrinsic connectivity networks showed dissociable correlations with functions measured outside the scanner. Prescan anxiety ratings correlated with intrinsic functional connectivity of the dACC node of the salience network, but with no region in the executive-control network, whereas executive task performance correlated with lateral parietal nodes of the executive-control network, but with no region in the salience network. Our findings suggest that task-free analysis of intrinsic connectivity networks may help elucidate the neural architectures that support fundamental aspects of human behavior.

Dissociable intrinsic connectivity networks for salience processing and executive control. Publishing Authors By Initials

WW Seeley,V Menon,AF Schatzberg,J Keller,GH Glover,H Kenna,AL Reiss,MD Greicius,

For similar psychological phenomena and processes: mental processes: thinking research abstracts see: psychological phenomena and processes: mental processes: thinking research

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Dissociable intrinsic connectivity networks for salience processing and executive control. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: The Journal of neuroscience : the official journal

VOLUME: 27

Page Numbers: 2349-56

Journal Abbreviation: J. Neurosci.

ISSN: 1529-2401

DAY: 28

MONTH: Feb

YEAR: 2007

Dissociable intrinsic connectivity networks for salience processing and executive control. Information

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LANGUAGE: eng

NlmUniqueID: 8102140

Dissociable intrinsic connectivity networks for salience processing and executive control. Keywords Mesh Terms:

KEYWORDS: Thinking

MESH TERMS: physiology

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Grant and Affiliation Information for Dissociable intrinsic connectivity networks for salience processing and executive control.

AFFILIATION: Department of Neurology, School of Medicine, University of California, San Francisco, San Francisco, California 94143, USa.

Country: United States

AGENCY: United States NCRR

GRANT: RR009784

ACRONYM: RR

MEDLINETA: J Neurosci

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