Disseminated cryptococcosis in HIV-uninfected patients.

Disseminated cryptococcosis in HIV-uninfected patients. Research Abstract Details 

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Disseminated cryptococcosis in HIV-uninfected patients. Abstract Text:

Cryptococcus neoformans usually causes disease in patients with human immunodeficiency virus (HIV) infection. This descriptive study was based on a retrospective review of 33 HIV-uninfected patients with disseminated cryptococcosis from 1998 to 2005. An underlying condition associated with immunocompromise was documented in 30 patients (90.9%), including liver cirrhosis (36.4%), diabetes mellitus (33.3%) and autoimmune disease (27.3%). Disseminated cryptococcosis carried a high mortality rate in this series, reaching 63% overall, with a median survival of 21 days. All patients (12/12) with liver cirrhosis died within the first month after the diagnosis of cryptococcosis. Otherwise, high Acute Physiology and Chronic Health Evaluation II (APACHE II) score, female gender and smoking history were associated with worse one-month outcome.

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Disseminated cryptococcosis in HIV-uninfected patients. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: European journal of clinical microbiology & infect

VOLUME: 27

Page Numbers: 307-10

Journal Abbreviation: Eur. J. Clin. Microbiol. Infec

ISSN: 0934-9723

DAY: 21

MONTH: Apr

YEAR: 2008

Disseminated cryptococcosis in HIV-uninfected patients. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Disseminated cryptococcosis in HIV-uninfected patients.

AFFILIATION: Department of Internal Medicine, National Taiwan University Hospital Yun-Lin Branch, Douliu, Taiwan.

Country: Germany

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MEDLINETA: Eur J Clin Microbiol Infect Di

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