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Disseminated crusted papules in a newborn.

Disseminated crusted papules in a newborn. Research Abstract Details 

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  • Disseminated crusted papules in a newborn. Abstract Text:

    milos d pavlovi?Milos D Pavlovi?,aleksandra mini?Aleksandra Mini?,lidija zolotarevskiLidija Zolotarevski,sonja vesi?Sonja Vesi?,

    BACKGROUND: Congenital self-healing Langerhans cell histiocytosis (Hashimoto-Pritzker disease) is the rarest form of Langerhans cell histiocytosis, usually confined to the skin and/or mucous membranes. Cutaneous eruption is mostly generalized, papular, nodular or vesicular. Despite impressive clinical presentation in a newborn it infrequently spreads to internal organs (which then portends a grave prognosis, indistinguishable from Letterer-Siwe disease). CASE REPORT: We presented a full-term newborn, female, 3.3 kg who had a multitude of erythematous and crusted papules, nodules and pseudovesicles distributed all over the body, except for the mucous membranes. A biopsy and haematoxylin--eosin stain revealed dermal infiltration of pleomorphic histiocytes with eosinophilic ground-glass cytoplasm and round to bean-shaped nuclei. Over the next six weeks the eruption gradually subsided leaving no residues, or a few atrophic scars. CONCLUSION: There is no need for specific treatment of congenital self-healing Langerhans cell-histiocytosis in the absence of multiorgan involvement. However, a close and regular follow-up is necessary to evaluate the children for systemic symptoms and signs.

    Disseminated crusted papules in a newborn. Publishing Authors By Initials

    md pavlovi?MD Pavlovi?,a mini?A Mini?,l zolotarevskiL Zolotarevski,s vesi?S Vesi?,

    For similar skin and connective tissue diseases: skin diseases research abstracts see: skin and connective tissue diseases: skin diseases research

    PUBMED ID PMID:

    MEDLINE DATE:

    Disseminated crusted papules in a newborn. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Vojnosanitetski pregled. Military-medical and phar

    VOLUME: 63

    Page Numbers: 681-3

    Journal Abbreviation:

    ISSN: 0042-8450

    DAY: 9

    MONTH: Jul

    YEAR: 2006

    Disseminated crusted papules in a newborn. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 21530700

    Disseminated crusted papules in a newborn. Keywords Mesh Terms:

    KEYWORDS: Skin Diseases

    MESH TERMS: pathology

    Chemical & Substance for Abstract: Disseminated crusted papules in a newborn. Information

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    Grant and Affiliation Information for Disseminated crusted papules in a newborn.

    AFFILIATION: Military Medical Academy, Clinic of Dermatology, Center of Pathology and Forensic Medicine, Belgrade. mdpavlovic2004@yahoo.com

    Country: Serbia and Montenegro

    Serbia and Montenegro Research PublicationSerbia and Montenegro Research Publication

    AGENCY:

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    ACRONYM:

    MEDLINETA: Vojnosanit Pregl

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