Dissecting cellular components of the secretory pathway in filamentous fungi: insights into their application for protein production.

Dissecting cellular components of the secretory pathway in filamentous fungi: insights into their application for protein production. Research Abstract Details 

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Dissecting cellular components of the secretory pathway in filamentous fungi: insights into their application for protein production. Abstract Text:

Jun-Ya Shoji,Manabu Arioka,Katsuhiko Kitamoto,

Studies on protein production using filamentous fungi have mostly focused on improvement of the protein yields by genetic modifications such as overexpression. Recent genome sequencing in several filamentous fungal species now enables more systematic approaches based on reverse genetics and molecular biology of the secretion pathway. In this review, we summarize recent molecular-based advances in our understanding of vesicular trafficking in filamentous fungi, and discuss insights into their high secretion ability and application for protein production.

Dissecting cellular components of the secretory pathway in filamentous fungi: insights into their application for protein production. Publishing Authors By Initials

JY Shoji,M Arioka,K Kitamoto,

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Dissecting cellular components of the secretory pathway in filamentous fungi: insights into their application for protein production. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Biotechnology letters

VOLUME: 30

Page Numbers: 7-14

Journal Abbreviation: Biotechnol. Lett.

ISSN: 0141-5492

DAY: 11

MONTH: 09

YEAR: 2007

Dissecting cellular components of the secretory pathway in filamentous fungi: insights into their application for protein production. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Dissecting cellular components of the secretory pathway in filamentous fungi: insights into their application for protein production.

AFFILIATION: Department of Biotechnology, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan, akitamo@mail.ecc.u-tokyo.ac.jp.

Country: Netherlands

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MEDLINETA: Biotechnol Lett

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