Discrete stochastic models for compliance analysis based on an AIDS Clinical Trial Group (ACTG) study.

Discrete stochastic models for compliance analysis based on an AIDS Clinical Trial Group (ACTG) study. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Discrete stochastic models for compliance analysis based on an AIDS Clinical Trial Group (ACTG) study. Abstract Text:

Junfeng Sun,H N Nagaraj,Nancy R Reynolds,Junfeng Sun,H N Nagaraj,Nancy R Reynolds,

Compliance is the extent to which a patient follows the prescribed regimen. Here we investigate the statistical properties of two popular measures of compliance - percentage of compliant days and percentage of doses taken. We use a stationary Markov chain to model the dependence structure of successive data points for each subject. We illustrate our model using discrete compliance data collected from an AIDS Clinical Trial Group study (ACTG 398). We check the model assumptions and evaluate the small sample as well as large sample properties of our estimators. We show that ignoring the within-subject dependence will usually underestimate the standard errors of the estimates of these compliance measures. Our model allows the application of meta-analytic approaches to assess the variation across subjects in these compliance indices and changes in them due to intervention.

Discrete stochastic models for compliance analysis based on an AIDS Clinical Trial Group (ACTG) study. Publishing Authors By Initials

J Sun,HN Nagaraj,NR Reynolds,J Sun,HN Nagaraj,NR Reynolds,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Discrete stochastic models for compliance analysis based on an AIDS Clinical Trial Group (ACTG) study. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Biometrical journal. Biometrische Zeitschrift

VOLUME: 49

Page Numbers: 731-41

Journal Abbreviation:

ISSN: 0323-3847

DAY: 16

MONTH: Aug

YEAR: 2007

Discrete stochastic models for compliance analysis based on an AIDS Clinical Trial Group (ACTG) study. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7708048

Discrete stochastic models for compliance analysis based on an AIDS Clinical Trial Group (ACTG) study. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Discrete stochastic models for compliance analysis based on an AIDS Clinical Trial Group (ACTG) study. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Discrete stochastic models for compliance analysis based on an AIDS Clinical Trial Group (ACTG) study.

AFFILIATION: Department of Biostatistics, College of Public Health, University of Nebraska Medical Center, 984375 Nebraska Medical Center, Omaha, NE 68 198-4375, USA. junfengsun@unmc.edu

Country: Germany

AGENCY: United States NINR

GRANT: R01NR05108

ACRONYM: NR

MEDLINETA: Biom J

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Discrete stochastic models for compliance analysis based on an AIDS Clinical Trial Group ACTG study Related Publications

• A description of the preterm fetal sheep systemic and central responses to maternal general anesthesia.
• A review of delay-discounting research with humans: relations to drug use and gambling.
• Accelerating lumbar fusions by combining rhBMP-2 with allograft bone: a prospective analysis of interbody fusion rates and clinical outcomes.
• Age-related differences in the lifestyle regularity of seniors experiencing bereavement, care-giving, insomnia, and advancement into old-old age.
• An Intent-to-Treat Method for Enhancing Analysis of Clinical Trials with Rescue Medication: A Mixed-Model Approach.
• Anne L. Davis, m.d.: 1925-2003.
• Barbaloin in aloe species.
• Birth characteristics and risk of neuroblastoma in young children.
• Bone morphogenetic protein type 2 receptor gene therapy attenuates hypoxic pulmonary hypertension.
• Effect of comorbid anxiety on treatment response and relapse risk in late-life depression: controlled study.
• Emergence, persistence, and resolution of suicidal ideation during treatment of depression in old age.
• Ethical considerations in the conduct of electronic surveillance research.
• Event perception: a mind-brain perspective.
• Expanding the usefulness of Interpersonal Psychotherapy (IPT) for depressed elders with co-morbid cognitive impairment.
• Feeding rumen-inert fats differing in their degree of saturation decreases intake and increases plasma concentrations of gut peptides in lactating dairy cows.
• Flow cytometric analysis of adherence of Porphyromonas gingivalis to oral epithelial cells.
• Hemlock Alkaloids in Aloes. Occurrence and Distribution of gamma-Coniceine.
• Improved oral delivery of N-(4-hydroxyphenyl)retinamide with a novel LYM-X-SORB organized lipid complex.
• Kgp and RgpB, but not RgpA, are important for Porphyromonas gingivalis virulence in the murine periodontitis model.
• Mitochondrial trafficking and morphology in healthy and injured neurons.
• Placental growth throughout the last two thirds of pregnancy in sheep: vascular development and angiogenic factor expression.
• Plasma concentrations of gut peptides in dairy cattle increase after calving.
• Sleep in healthy seniors: a diary study of the relation between bedtime and the amount of sleep obtained.
• Stimulus-specific competitive selection in macaque extrastriate visual area V4.
• Synthesis and biological evaluation of thiazolidine-2-one 1,1-dioxide as inhibitors of Escherichia coli beta-ketoacyl-ACP-synthase III (FabH).
• Temporal resolution for the perception of features and conjunctions.
• The Opi1p transcription factor affects expression of FLO11, mat formation, and invasive growth in Saccharomyces cerevisiae.
• Vaccination with recombinant adhesins from the RgpA-Kgp proteinase-adhesin complex protects against Porphyromonas gingivalis infection.
• p120-catenin and p190RhoGAP regulate cell-cell adhesion by coordinating antagonism between Rac and Rho.
• p120-catenin: Past and present.