Direct One-Pot Synthesis of Phenanthrenes via Suzuki-Miyaura Coupling/Aldol Condensation Cascade Reaction.

Direct One-Pot Synthesis of Phenanthrenes via Suzuki-Miyaura Coupling/Aldol Condensation Cascade Reaction. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Direct One-Pot Synthesis of Phenanthrenes via Suzuki-Miyaura Coupling/Aldol Condensation Cascade Reaction. Abstract Text:

Young Ha Kim,Hyuk Lee,Yeong Joon Kim,Bum Tae Kim,Jung-Nyoung Heo,Young Ha Kim,Hyuk Lee,Yeong Joon Kim,Bum Tae Kim,Jung-Nyoung Heo,Young Ha Kim,Hyuk Lee,Yeong Joon Kim,Bum Tae Kim,Jung-Nyoung Heo,

We have developed an efficient cascade reaction, a Suzuki-Miyaura coupling followed by an aldol condensation, for the construction of phenanthrene derivatives using microwave irradiation. For example, the reaction of methyl 2-bromophenylacetamide with 2-formylphenylboronic acid in the presence of a palladium catalyst and a base provided a biaryl intermediate, which underwent in situ cyclization to afford the corresponding phenanthrene in high yield.

Direct One-Pot Synthesis of Phenanthrenes via Suzuki-Miyaura Coupling/Aldol Condensation Cascade Reaction. Publishing Authors By Initials

YH Kim,H Lee,YJ Kim,BT Kim,JN Heo,YH Kim,H Lee,YJ Kim,BT Kim,JN Heo,YH Kim,H Lee,YJ Kim,BT Kim,JN Heo,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Direct One-Pot Synthesis of Phenanthrenes via Suzuki-Miyaura Coupling/Aldol Condensation Cascade Reaction. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: The Journal of organic chemistry

VOLUME: 73

Page Numbers: 495-501

Journal Abbreviation: J. Org. Chem.

ISSN: 0022-3263

DAY: 23

MONTH: 12

YEAR: 2007

Direct One-Pot Synthesis of Phenanthrenes via Suzuki-Miyaura Coupling/Aldol Condensation Cascade Reaction. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 2985193

Direct One-Pot Synthesis of Phenanthrenes via Suzuki-Miyaura Coupling/Aldol Condensation Cascade Reaction. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Direct One-Pot Synthesis of Phenanthrenes via Suzuki-Miyaura Coupling/Aldol Condensation Cascade Reaction. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Direct One-Pot Synthesis of Phenanthrenes via Suzuki-Miyaura Coupling/Aldol Condensation Cascade Reaction.

AFFILIATION: The Center for Medicinal Chemistry, Korea Research Institute of Chemical Technology, 100 Jang-dong, Daejeon 305-600, Korea, and Department of Chemistry, Chungnam National University, 220 Gung-dong, Daejeon 305-764, Korea.

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: J Org Chem

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Direct One-Pot Synthesis of Phenanthrenes via Suzuki-Miyaura Coupling/Aldol Condensation Cascade Reaction Related Publications

• Aggressiveness of cancer-care near the end-of-life in Korea.
• Antioxidant and antigenotoxic activities of Korean fermented soybean.
• Biological screening of 100 plant extracts for cosmetic use (II): anti-oxidative activity and free radical scavenging activity.
• Chemotherapy use and associated factors among cancer patients near the end of life.
• Chronic cerebral hypoperfusion protects against acute focal ischemia, improves motor function, and results in vascular remodeling.
• Crystal structure of the biotin carboxylase domain of human acetyl-CoA carboxylase 2.
• Direct One-Pot Synthesis of Phenanthrenes via Suzuki-Miyaura Coupling/Aldol Condensation Cascade Reaction.
• Dynamic CT of portal hypertensive gastropathy: significance of transient gastric perfusion defect sign.
• Efficacy of chemotherapy as a first-line treatment in ocular adnexal extranodal marginal zone B-cell lymphoma.
• Factors influencing medication adherence in patients with heart failure.
• Frequency and significance of cardiac sources of embolism in the TOAST classification.
• High tumour islet macrophage infiltration correlates with improved patient survival but not with EGFR mutations, gene copy number or protein expression in resected non-small cell lung cancer.
• Long-term survival of resectable subset after induction chemotherapy in patients with locally advanced head and neck cancer.
• Mechanism of infarction involving ipsilateral carotid and posterior cerebral artery territories.
• Molecular characterization and genogrouping of VP1 of aquatic birnavirus GC1 isolated from rockfish Sebastes schlegeli in Korea.
• Multicenter phase II trial of Genexol-PM, a novel Cremophor-free, polymeric micelle formulation of paclitaxel, with cisplatin in patients with advanced non-small-cell lung cancer.
• Nonsurgical treatment of an incompletely excised primary adenocarcinoma of nonpigmented ciliary epithelium.
• Palliative chemotherapy for pulmonary pleomorphic carcinoma.
• Placebo response and antidepressant response.
• Projected prevalence of US adults with self-reported doctor-diagnosed arthritis, 2005 to 2050.
• Rapidly induced selective cerebral hypothermia using a cold carotid arterial flush during cardiac arrest in a dog model.
• Sequential analysis applied to clinical trials in dentistry: a systematic review.
• Sequential combination of intravenous recombinant tissue plasminogen activator and intra-arterial urokinase in acute ischemic stroke.
• Simple microwire and microcatheter mechanical thrombolysis with adjuvant intraarterial urokinase for treatment of hyperacute ischemic stroke patients.
• Solidification and recycling of incinerator bottom ash through the addition of colloidal silica (SiO2) solution.
• Suitability of macrophage inflammatory protein-1beta production by THP-1 cells in differentiating skin sensitizers from irritant chemicals.
• Thrombus Volume Comparison between Patients with and without Hyperattenuated Artery Sign on CT.
• Total Synthesis of Aristolactams via a One-Pot Suzuki-Miyaura Coupling/Aldol Condensation Cascade Reaction.
• [The attitudes of nurses toward transsexuals]
• [The efficacy of sorafenib for patients with advanced hepatocellular carcinoma.]