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Diminishing returns in sequential interventions of gastroenterology.

Diminishing returns in sequential interventions of gastroenterology. Research Abstract Details 

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  • Diminishing returns in sequential interventions of gastroenterology. Abstract Text:

    Gastroenterological treatment is often comprised of a series of multiple interventions, each one associated with a potential benefit, as well as harm. The analysis addresses the question of when to stop a series of consecutive interventions and maximize medical benefit. The benefit and harm associated with gastroenterological interventions are modeled as 'continuous' influences on patient health or as a 'discrete' sequence of random events. The analysis suggests that the benefit of a sequence of gastroenterological interventions is likely to accumulate following few interventions at the beginning of therapy and that any prolonged sequence is likely to inflict as much harm as benefit. It is impossible to reach a state of perfect health with inherently imperfect interventions. Health cannot be raised above a level that equals the ratio of expected benefit/(expected benefit+expected harm). As the achievement of perfect health constitutes an unattainable goal, a sequence of gastroenterological interventions should not be continued much further beyond its initial success.

    Diminishing returns in sequential interventions of gastroenterology. Publishing Authors By Initials

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    PUBMED ID PMID:

    MEDLINE DATE:

    Diminishing returns in sequential interventions of gastroenterology. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: European journal of gastroenterology & hepatology

    VOLUME: 20

    Page Numbers: 465-8

    Journal Abbreviation:

    ISSN: 0954-691X

    DAY: 11

    MONTH: May

    YEAR: 2008

    Diminishing returns in sequential interventions of gastroenterology. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 9000874

    Diminishing returns in sequential interventions of gastroenterology. Keywords Mesh Terms:

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    Grant and Affiliation Information for Diminishing returns in sequential interventions of gastroenterology.

    AFFILIATION: Portland VA Medical Center and Oregon Health and Science University, Portland, Oregon, USA.

    Country: England

    England Research PublicationEngland Research Publication

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    MEDLINETA: Eur J Gastroenterol Hepatol

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