Diffusion-weighted imaging in normal fetal brain maturation.

Diffusion-weighted imaging in normal fetal brain maturation. Research Abstract Details 

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Diffusion-weighted imaging in normal fetal brain maturation. Abstract Text:

J F Schneider,S Confort-Gouny,Y Le Fur,P Viout,M Bennathan,F Chapon,C Fogliarini,P Cozzone,N Girard,J F Schneider,S Confort-Gouny,Y Le Fur,P Viout,M Bennathan,F Chapon,C Fogliarini,P Cozzone,N Girard,

Diffusion-weighted imaging (DWI) provides information about tissue maturation not seen on conventional magnetic resonance imaging. The aim of this study is to analyze the evolution over time of the apparent diffusion coefficient (ADC) of normal fetal brain in utero. DWI was performed on 78 fetuses, ranging from 23 to 37 gestational weeks (GW). All children showed at follow-up a normal neurological evaluation. ADC values were obtained in the deep white matter (DWM) of the centrum semiovale, the frontal, parietal, occipital and temporal lobe, in the cerebellar hemisphere, the brainstem, the basal ganglia (BG) and the thalamus. Mean ADC values in supratentorial DWM areas (1.68 +/- 0.05 mm(2)/s) were higher compared with the cerebellar hemisphere (1.25 +/- 0.06 mm(2)/s) and lowest in the pons (1.11 +/- 0.05 mm(2)/s). Thalamus and BG showed intermediate values (1.25 +/- 0.04 mm(2)/s). Brainstem, cerebellar hemisphere and thalamus showed a linear negative correlation with gestational age. Supratentorial areas revealed an increase in ADC values, followed by a decrease after the 30th GW. This study provides a normative data set that allows insights in the normal fetal brain maturation in utero, which has not yet been observed in previous studies on premature babies.

Diffusion-weighted imaging in normal fetal brain maturation. Publishing Authors By Initials

JF Schneider,S Confort-Gouny,Y Le Fur,P Viout,M Bennathan,F Chapon,C Fogliarini,P Cozzone,N Girard,JF Schneider,S Confort-Gouny,Y Le Fur,P Viout,M Bennathan,F Chapon,C Fogliarini,P Cozzone,N Girard,

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Diffusion-weighted imaging in normal fetal brain maturation. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: European radiology

VOLUME: 17

Page Numbers: 2422-9

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ISSN: 0938-7994

DAY: 3

MONTH: 04

YEAR: 2007

Diffusion-weighted imaging in normal fetal brain maturation. Information

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LANGUAGE: eng

NlmUniqueID: 9114774

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Grant and Affiliation Information for Diffusion-weighted imaging in normal fetal brain maturation.

AFFILIATION: Department of Pediatric Radiology, University Children's Hospital UKBB, Basel, Switzerland. jacques.schneider@ukbb.ch

Country: Germany

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MEDLINETA: Eur Radiol

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