Diffusion MR imaging techniques are based on the molecular mobility of water, which is sensitive to interaction with intracellular elements, macromolecules, cell membranes, the density of cells, and microstructural organization. Disease processes that alter cell-water homeostasis, cell density, and cytoarchitecture affect water mobility and are quantifiable by diffusion MR imaging methodologies. Similarly, therapeutic intervention that alters these properties may be monitored for efficacy via diffusion MR imaging. This article outlines basic technical concepts and applications of diffusion imaging with an emphasis on oncology.
Diffusion imaging: insight to cell status and cytoarchitecture. Publishing Authors By Initials
Diffusion imaging: insight to cell status and cytoarchitecture. Journal Published:
PUBLICATION TYPE: Review
Journal: Neuroimaging clinics of North America
VOLUME: 16
Page Numbers: 619-32, viii-ix
Journal Abbreviation: Neuroimaging Clin. N. Am.
ISSN: 1052-5149
DAY: 3
MONTH: Nov
YEAR: 2006
Diffusion imaging: insight to cell status and cytoarchitecture. Information
Number of References: 81
LANGUAGE: eng
NlmUniqueID: 9211377
Diffusion imaging: insight to cell status and cytoarchitecture. Keywords Mesh Terms:
KEYWORDS: Humans
MESH TERMS: therapy
Chemical & Substance for Abstract: Diffusion imaging: insight to cell status and cytoarchitecture. Information
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Grant and Affiliation Information for Diffusion imaging: insight to cell status and cytoarchitecture.
AFFILIATION: Department of Radiology, University of Michigan Health Systems, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA. tlchenev@umich.edu
Country: United States
AGENCY: United States NCI
GRANT: P01 CA 85878
ACRONYM: CA
MEDLINETA: Neuroimaging Clin N Am
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