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Differential Regulation of Ecdysteroidogenic P450 Gene Expression in the Silkworm, Bombyx mori.

Differential Regulation of Ecdysteroidogenic P450 Gene Expression in the Silkworm, Bombyx mori. Research Abstract Details 

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  • Differential Regulation of Ecdysteroidogenic P450 Gene Expression in the Silkworm, Bombyx mori. Abstract Text:

    naoki yamanakaNaoki Yamanaka,naoko hondaNaoko Honda,noe osatoNoe Osato,ryusuke niwaRyusuke Niwa,akira mizoguchiAkira Mizoguchi,hiroshi kataokaHiroshi Kataoka,naoki yamanakaNaoki Yamanaka,naoko hondaNaoko Honda,noe osatoNoe Osato,ryusuke niwaRyusuke Niwa,akira mizoguchiAkira Mizoguchi,hiroshi kataokaHiroshi Kataoka,naoki yamanakaNaoki Yamanaka,naoko hondaNaoko Honda,noe osatoNoe Osato,ryusuke niwaRyusuke Niwa,akira mizoguchiAkira Mizoguchi,hiroshi kataokaHiroshi Kataoka,

    The regulatory mechanisms of ecdysteroidogenic P450 gene expression were investigated in the silkworm, Bombyx mori. Bommo-FMRFamide (BRFa), a neural suppressor of prothoracic gland (PG) activity, was found to suppress the expression of several P450 genes induced by prothoracicotropic hormone (PTTH) in the PG. A transcription inhibitor suppressed PTTH-induced expression of the P450 genes and the opposing effects of BRFa, while their short-term effects on ecdysteroidogenesis remained unchanged. This result suggests that the effects of these factors on the P450 gene transcripts become obvious on a longer time scale. Moreover, spontaneous expression of a P450 gene was observed in long-term PG culture, and was repressed by juvenile hormone. These results explain well the developmental fluctuation patterns of the P450 gene transcripts in the PG, indicating that multiple factors coordinate to regulate basal PG activity during insect development.

    Differential Regulation of Ecdysteroidogenic P450 Gene Expression in the Silkworm, Bombyx mori. Publishing Authors By Initials

    n yamanakaN Yamanaka,n hondaN Honda,n osatoN Osato,r niwaR Niwa,a mizoguchiA Mizoguchi,h kataokaH Kataoka,n yamanakaN Yamanaka,n hondaN Honda,n osatoN Osato,r niwaR Niwa,a mizoguchiA Mizoguchi,h kataokaH Kataoka,n yamanakaN Yamanaka,n hondaN Honda,n osatoN Osato,r niwaR Niwa,a mizoguchiA Mizoguchi,h kataokaH Kataoka,

    For similar abstracts research abstracts see: abstracts research

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    Differential Regulation of Ecdysteroidogenic P450 Gene Expression in the Silkworm, Bombyx mori. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Bioscience, biotechnology, and biochemistry

    VOLUME: 71

    Page Numbers: 2808-14

    Journal Abbreviation: Biosci. Biotechnol. Biochem.

    ISSN: 0916-8451

    DAY: 7

    MONTH: 11

    YEAR: 2007

    Differential Regulation of Ecdysteroidogenic P450 Gene Expression in the Silkworm, Bombyx mori. Information

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    LANGUAGE: eng

    NlmUniqueID: 9205717

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    Grant and Affiliation Information for Differential Regulation of Ecdysteroidogenic P450 Gene Expression in the Silkworm, Bombyx mori.

    AFFILIATION: Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo.

    Country: Japan

    Japan Research PublicationJapan Research Publication

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    MEDLINETA: Biosci Biotechnol Biochem

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