Differences in substrate selectivities of the SPOUT superfamily of methyltransferases.

Differences in substrate selectivities of the SPOUT superfamily of methyltransferases. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Differences in substrate selectivities of the SPOUT superfamily of methyltransferases. Abstract Text:

Takashi Toyooka,Hiroyuki Hori,

Since the SPOUT superfamily was defined by homology between the SpoU and TrmD families [Anantharaman, V. et al., J. Mol. Microbiol. Biotechnol., 4, 71-75 (2002)], many crystal structures have been solved and numerous new homologous sequences have been found in the superfamily. Therefore, nowadays, we can consider enzyme function and/or evolution process of the SPOUT superfamily members using not only amino acid sequences but also protein structures. Recently, a bioinformatics research on SPOUT superfamily proposed existences of new member proteins [COG1756, COG1772, COG4080, and COG1901], and provided a structural and evolutionary classification of the proteins [Tkaczuk, K.L. et al., BMC Bioinformatics, 8:73 (2007)], which serves as a guide for studies on the SPOUT family in future. In this meeting, we report a new approach using a flexible protein structure alignment algorithm (FATCAT) to analyze the structures of SPOUT superfamily proteins, and discuss differences in substrate selectivities of methyltransferases in the superfamily.

Differences in substrate selectivities of the SPOUT superfamily of methyltransferases. Publishing Authors By Initials

T Toyooka,H Hori,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Differences in substrate selectivities of the SPOUT superfamily of methyltransferases. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Nucleic acids symposium series (2004)

VOLUME:

Page Numbers: 445-6

Journal Abbreviation: Nucleic Acids Symp Ser (Oxf)

ISSN: 1746-8272

DAY: 21

MONTH: 11

YEAR: 2007

Differences in substrate selectivities of the SPOUT superfamily of methyltransferases. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 101259965

Differences in substrate selectivities of the SPOUT superfamily of methyltransferases. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Differences in substrate selectivities of the SPOUT superfamily of methyltransferases. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Differences in substrate selectivities of the SPOUT superfamily of methyltransferases.

AFFILIATION: Department of Materials Science and Biotechnology, Graduate School of Science and Engineering Ehime University, Bunkyo 3 Matuyama 790-8577, Japan.

Country: England

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Nucleic Acids Symp Ser (Oxf)

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Differences in substrate selectivities of the SPOUT superfamily of methyltransferases Related Publications

• A dibenzoylmethane derivative protects dopaminergic neurons against both oxidative stress and endoplasmic reticulum stress.
• A smart video magnifier controlled by the visibility signal of a low vision user.
• Adrenodoxin-cytochrome P450scc interaction as revealed by EPR spectroscopy: comparison with the putidaredoxin-cytochrome P450cam system.
• Compact synchrotron light source of the HSRC.
• Determination of nonylphenol ethoxylates and octylphenol ethoxylates in environmental samples using 13C-labeled surrogate compounds.
• Differences in substrate selectivities of the SPOUT superfamily of methyltransferases.
• Drug-resistance gene expression and progression of astrocytic tumors.
• Effect of combined humanPTH(1-34) and calcitonin treatment in ovariectomized rats.
• Effect of intracoronary thrombectomy on 30-day mortality in patients with acute myocardial infarction.
• Effect of molecular chirality and side chain bulkiness on angiogenesis of haloacetylcarbamoyl-2-nitroimidazole compounds.
• Effect on Outcome of an Increase of Serum Cardiac Troponin T in Patients With Healing or Healed ST-Elevation Myocardial Infarction.
• Enhancement of synaptic transmission and nociceptive behaviour in HPC-1/syntaxin 1A knockout mice following peripheral nerve injury.
• Hetero subunit interaction and RNA recognition of yeast tRNA (m7G46) methyltransferase synthesized in a wheat germ cell-free translation system.
• Hydroxyl radical probing of tRNA (Gm18) methyltransferase [TrmH]-AdoMet-artificial tRNA ternary complex.
• Influence of the signal-to-noise ratio on the accuracy of IOLMaster measurements.
• Isolation of diacylglycerol-2-aminoethylphosphonate from Tetrahymena pyriformis.
• Long-term oral administration of dipyridamole improves both cardiac and physical status in patients with mild to moderate chronic heart failure: a prospective open-randomized study.
• Modified permanent middle cerebral artery occlusion rat model aiming to reduce variability in infarct size.
• Motor evoked potential mapping and monitoring by direct brainstem stimulation. Technical note.
• Nicardipine prolonged-release implants for preventing cerebral vasospasm after subarachnoid hemorrhage: effect and outcome in the first 100 patients.
• Perioperative plasma active and total ghrelin levels are reduced in acromegaly when compared with in nonfunctioning pituitary tumours even after normalization of serum GH.
• Rho-kinase activation in endothelial cells contributes to expansion of infarction after focal cerebral ischemia.
• Right-handed snakes: convergent evolution of asymmetry for functional specialization.
• Selective peripheral denervation of the levator scapulae muscle for laterocollic cervical dystonia.
• Sequence motif-specific assignment of two [2Fe-2S] clusters in rat xanthine oxidoreductase studied by site-directed mutagenesis.
• The carboxyl-terminus directs TAF(I)48 to the nucleus and nucleolus and associates with multiple nuclear import receptors.
• Vertebrate collagenase: direct extraction from animal skin and human synovial membrane.
• Visual emotional context modulates brain potentials elicited by unattended tones.
• [Current status and problems in approval of new anticancer drugs in Japan]
• [Jervell and Lange-Nielsen syndrome]