Differences in characteristics among 1,000 women with endometriosis based on extent of disease.

Differences in characteristics among 1,000 women with endometriosis based on extent of disease. Research Abstract Details 

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Differences in characteristics among 1,000 women with endometriosis based on extent of disease. Abstract Text:

Ninet Sinaii,Katherine Plumb,Louise Cotton,Ann Lambert,Stephen Kennedy,Krina Zondervan,Pamela Stratton,

OBJECTIVE: To determine the relationship between disease severity and patient characteristics in endometriosis. DESIGN: Cross-sectional study of self-reported survey data. SETTING: Academic research setting. PATIENT(S): One thousand women in the Oxford Endometriosis Gene (OXEGENE) study. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Participants were assigned to one of two groups with predominantly revised AFS stage I-II (group I, n = 423) or III-IV disease (group II, n = 517). Their characteristics were compared by disease extent. RESULT(S): Most participants were white (96%) and of reproductive age (81%). Women in group I were significantly younger on entering the study (39.9 +/- 0.5 vs. 44.5 +/- 0.4 years). Overall time to diagnosis did not differ between groups. The most common symptoms leading to a diagnosis were dysmenorrhea (79%) and pelvic pain (69%). In group II, subfertility (21.5% vs. 30.0%) and an ovarian mass (7.3% vs. 29.4%) more commonly led to a diagnosis, whereas dyspareunia (51.1% vs. 39.5%) was significantly more common in group I. Subfertility (41.5% vs. 53.4%) remained more common in group II throughout reproductive life, although birth and miscarriage rates were similar. CONCLUSION(S): Pelvic pain is common to all with endometriosis and those with more extensive disease report higher rates of subfertility. Remarkably, the time to diagnosis was similar among women.

Differences in characteristics among 1,000 women with endometriosis based on extent of disease. Publishing Authors By Initials

N Sinaii,K Plumb,L Cotton,A Lambert,S Kennedy,K Zondervan,P Stratton,

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Differences in characteristics among 1,000 women with endometriosis based on extent of disease. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Intr

Journal: Fertility and sterility

VOLUME: 89

Page Numbers: 538-45

Journal Abbreviation: Fertil. Steril.

ISSN: 1556-5653

DAY: 11

MONTH: 05

YEAR: 2007

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LANGUAGE: eng

NlmUniqueID: 372772

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AFFILIATION: Biostatistics and Clinical Epidemiology Service, Clinical Center, National Institutes of Health, Bethesda, Maryland 20892-1871, USA. sinaiin@mail.nih.gov

Country: United States

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MEDLINETA: Fertil Steril

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