Difference in celiac disease risk between Swedish birth cohorts suggests an opportunity for primary prevention.

Difference in celiac disease risk between Swedish birth cohorts suggests an opportunity for primary prevention. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Difference in celiac disease risk between Swedish birth cohorts suggests an opportunity for primary prevention. Abstract Text:

OBJECTIVES. Sweden experienced a unique epidemic of celiac disease in children <2 years of age. The epidemic was partly explained by changes in infant feeding over time and indicated a multifactorial pathogenesis. The main aim of this study was to analyze celiac disease risk in epidemic and postepidemic birth cohorts up to preschool age, to explore further the opportunity for primary prevention. METHODS. A population-based incidence register of celiac disease in children covering the entire nation from 1998 to 2003 and part of the country back to 1973 was analyzed. European Society for Pediatric Gastroenterology, Hepatology, and Nutrition diagnostic criteria for celiac disease were used. The annual incidence rate for each age group and the cumulative incidence according to age for each birth cohort were calculated. RESULTS. A considerable difference in cumulative incidences of celiac disease at comparable ages was demonstrated between birth cohorts from the epidemic and postepidemic periods. The difference persisted during the preschool years, although it decreased somewhat with age. During the last years of the follow-up period, there was again a successive increase in incidence rate among children <2 years of age. CONCLUSIONS. The difference in celiac disease risk between birth cohorts at comparable ages suggests an opportunity for primary prevention. This highlights the importance of further exploring the role of infant feeding and exogenous factors besides dietary gluten that might initiate or prevent disease development. Moreover, on the basis of postepidemic incidence trends, we speculate that the Swedish epidemic might not have been as unique as thought previously, although its magnitude was striking.

Difference in celiac disease risk between Swedish birth cohorts suggests an opportunity for primary prevention. Publishing Authors By Initials

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Difference in celiac disease risk between Swedish birth cohorts suggests an opportunity for primary prevention. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Pediatrics

VOLUME: 122

Page Numbers: 528-34

Journal Abbreviation: Pediatrics

ISSN: 1098-4275

DAY: 2

MONTH: Sep

YEAR: 2008

Difference in celiac disease risk between Swedish birth cohorts suggests an opportunity for primary prevention. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 376422

Difference in celiac disease risk between Swedish birth cohorts suggests an opportunity for primary prevention. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Difference in celiac disease risk between Swedish birth cohorts suggests an opportunity for primary prevention. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Difference in celiac disease risk between Swedish birth cohorts suggests an opportunity for primary prevention.

AFFILIATION: RD, Department of Food and Nutrition, Umeå University, SE-901 87 Umeå, Sweden. cecilia.olsson@kost.umu.se.

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Pediatrics

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Difference in celiac disease risk between Swedish birth cohorts suggests an opportunity for primary prevention Related Publications

• A local imbalance between MMP and TIMP may have an implication on the severity and course of appendicitis.
• A new impedance method for measuring middle ear mechanics and eustachian tube function.
• A prospective comparison of Butel and PCA hip arthroplasty.
• Acetabular revision with extensive allograft impaction and uncemented hydroxyapatite-coated implants. Results after 9 (7-11) years follow-up.
• Advantages of doubly polished thin sections for the study of microfossils in volcanic rock.
• Antacids and H2-receptor antagonists in the prophylaxis and treatment of erosive gastritis: clinical aspects.
• Can growth hormone treatment increase final height in constitutional short stature?
• Difference in celiac disease risk between Swedish birth cohorts suggests an opportunity for primary prevention.
• Increased TGF-Beta1 protein expression in patients with advanced colorectal cancer.
• Inhibition of the inferior olive during conditioned responses in the decerebrate ferret.
• Intraoperative measurements of gastric blood flow in man: effects on blood flow of acid secretory stimulation and inhibition.
• Maternal Enterovirus Infection during Pregnancy as a Risk Factor in Offspring Diagnosed with Type 1 Diabetes between 15 and 30 Years of Age.
• No difference in migration or wear between cemented low-profile cups and standard cups : a randomized radiostereographic study of 53 patients over 3 years.
• Number of islet autoantibodies present in newly diagnosed type 1 diabetes children born to non-diabetic mothers is affected by islet autoantibodies present at birth.
• Occupation as described by novice occupational therapy students in Sweden: the first step in a theory generative process grounded in empirical data.
• Older women with a serious cardiac event experience support with a Vifladt & Hopen inspired patient group education programme.
• Pulmonary metastasis formation after intravenous tumour cell injection in defibrinogenated rats.
• Pulmonary metastasis formation after trauma.
• Some anthropological aspects of the climacteric syndrome.
• Stereological analysis of coated pits and secondary lysosomes in cultured human glial and glioma cells.
• Transforming growth factor beta-1 in rectal tumour, mucosa and plasma in relation to radiotherapy and clinical outcome in rectal cancer patients.
• Tumor classification by electron microscopy of fine needle aspiration biopsy material.