Dietary calcium and magnesium, major food sources, and risk of type 2 diabetes in U.S. black women.

Dietary calcium and magnesium, major food sources, and risk of type 2 diabetes in U.S. black women. Research Abstract Details 

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Dietary calcium and magnesium, major food sources, and risk of type 2 diabetes in U.S. black women. Abstract Text:

Rob M van Dam,Frank B Hu,Lynn Rosenberg,Supriya Krishnan,Julie R Palmer,

OBJECTIVE: Inverse associations between magnesium and calcium intakes and risk of type 2 diabetes have been reported for studies in predominantly white populations. We examined magnesium, calcium, and major food sources in relation to type 2 diabetes in African-American women. RESEARCH DESIGN AND METHODS: This is a prospective cohort study including 41,186 participants of the Black Women's Health Study without a history of diabetes who completed validated food frequency questionnaires at baseline. During 8 years of follow-up (1995-2003), we documented 1,964 newly diagnosed cases of type 2 diabetes. RESULTS: The multivariate-adjusted hazard ratio of type 2 diabetes for the highest compared with the lowest quintile of intake was 0.69 (95% CI 0.59-0.81; P trend <0.0001) for dietary magnesium and 0.86 (0.74-1.00; P trend = 0.01) for dietary calcium. After mutual adjustment, the association for calcium disappeared (hazard ratio 1.04 [95% CI 0.88-1.24]; P trend = 0.88), whereas the association for magnesium remained. Daily consumption of low-fat dairy (0.87 [0.76-1.00]; P trend = 0.04) and whole grains (0.69 [0.60-0.79]; P trend <0.0001) were associated with a lower risk of type 2 diabetes compared with a consumption less than once a week. After mutual adjustment, the hazard ratio was 0.81 (0.68-0.97; P trend = 0.02) for magnesium and 0.73 (0.63-0.85; P trend <0.0001) for whole grains. CONCLUSIONS: These findings indicate that a diet high in magnesium-rich foods, particularly whole grains, is associated with a substantially lower risk of type 2 diabetes in U.S. black women.

Dietary calcium and magnesium, major food sources, and risk of type 2 diabetes in U.S. black women. Publishing Authors By Initials

RM van Dam,FB Hu,L Rosenberg,S Krishnan,JR Palmer,

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Dietary calcium and magnesium, major food sources, and risk of type 2 diabetes in U.S. black women. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Diabetes care

VOLUME: 29

Page Numbers: 2238-43

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ISSN: 0149-5992

DAY: 3

MONTH: Oct

YEAR: 2006

Dietary calcium and magnesium, major food sources, and risk of type 2 diabetes in U.S. black women. Information

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LANGUAGE: eng

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AFFILIATION: Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave., Boston, MA 02115, USA. rvandam@hsph.harvard.edu

Country: United States

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MEDLINETA: Diabetes Care

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