Diarylheptanoids from the rhizomes of Alpinia officinarum and their anticancer activity.

Diarylheptanoids from the rhizomes of Alpinia officinarum and their anticancer activity. Research Abstract Details 

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Diarylheptanoids from the rhizomes of Alpinia officinarum and their anticancer activity. Abstract Text:

Ning An,Zhong-Mei Zou,Ze Tian,Xiu-Zhen Luo,Shi-Lin Yang,Li-Zhen Xu,

Two new diarylheptanoids (1, 2), together with two known analogs (3, 4), were isolated from the rhizomes of Alpinia officinarum. The new compounds were elucidated to be (5S)-5-hydroxy-7-(3, 4-dihydroxyphenyl)-1-phenyl-3-heptanone (1) and (5R)-5-hydroxy-7-(3-methoxy-4, 5-dihydroxyphenyl)-1-phenyl-3-heptanone (2) based on their spectral analysis. Compound 4 showed moderate cytotoxicity against human tumor cell lines, HepG2, MCF-7 and SF-268, while no significant effect were found for compounds 1-3.

Diarylheptanoids from the rhizomes of Alpinia officinarum and their anticancer activity. Publishing Authors By Initials

N An,ZM Zou,Z Tian,XZ Luo,SL Yang,LZ Xu,

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Diarylheptanoids from the rhizomes of Alpinia officinarum and their anticancer activity. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Fitoterapia

VOLUME: 79

Page Numbers: 27-31

Journal Abbreviation: Fitoterapia

ISSN: 0367-326X

DAY: 9

MONTH: 08

YEAR: 2007

Diarylheptanoids from the rhizomes of Alpinia officinarum and their anticancer activity. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Diarylheptanoids from the rhizomes of Alpinia officinarum and their anticancer activity.

AFFILIATION: Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100094, China.

Country: Netherlands

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MEDLINETA: Fitoterapia

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