Diagnostic usefulness of postexercise systolic blood pressure response for detection of coronary artery disease in patients with echocardiographic left ventricular hypertrophy.

Diagnostic usefulness of postexercise systolic blood pressure response for detection of coronary artery disease in patients with echocardiographic left ventricular hypertrophy. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Diagnostic usefulness of postexercise systolic blood pressure response for detection of coronary artery disease in patients with echocardiographic left ventricular hypertrophy. Abstract Text:

Kiyoyasu Yamada,Makoto Hirai,Kazunari Abe,Hitoshi Ishihara,Kyosuke Takeshita,Yasunobu Takada,Masahiro Mutoh,Hironori Noda,Atsuya Shimizu,Yoshihisa Shibata,Takumi Yamada,Takahisa Kondo,Yukihiko Yoshida,Yasuya Inden,Toyoaki Murohara,

BACKGROUND: Although exercise-induced electrocardiographic ST segment changes are used to detect coronary artery disease (CAD), their diagnostic value is markedly decreased in patients with left ventricular (LV) hypertrophy. There have been no reports concerning postexercise systolic blood pressure (SBP) response in patients with ultrasound echocardiographic (UCG) LV hypertrophy and CAD. METHODS: Sixty-six patients with both UCG-LV hypertrophy (LV mass index 134 g/m2 or greater for men or 110 g/m2 or greater for women) and positive ST depression of at least 0.1 mV during treadmill exercise testing were studied. Coronary cineangiograms showed normal coronary arteries in 19 patients (group 1) and significant CAD in 47 patients (group 2). The SBP ratio was calculated by dividing the SBP 3 min after exercise (3 min SBP) by the SBP at peak exercise (peak SBP). RESULTS: There were no significant differences between the two groups in LV mass index, SBP at rest, exercise duration, ST depression (at rest and exercise-induced) or 3 min SBP. However, the SBP ratio was significantly higher in group 2 compared with group 1 (0.87+/-0.11 versus 1.01+/-0.18; P=0.004). Analysis of relative cumulative frequency distributions revealed an SBP ratio of 0.92 as the cutoff point for distinguishing a UCG-LV hypertrophy patient with CAD from one without CAD. The sensitivity, specificity and accuracy with an SBP ratio of 0.92 and an ST segment depression of at least 0.1 mV on treadmill exercise testing for detecting CAD in patients with UCG-LV hypertrophy were 77%, 74% and 76%, respectively. CONCLUSION: These findings suggest that the ratio of early post-exercise SBP to peak exercise SBP may be diagnostically useful in detecting CAD in patients with positive ST depression during an exercise test and UCG-LV hypertrophy.

Diagnostic usefulness of postexercise systolic blood pressure response for detection of coronary artery disease in patients with echocardiographic left ventricular hypertrophy. Publishing Authors By Initials

K Yamada,M Hirai,K Abe,H Ishihara,K Takeshita,Y Takada,M Mutoh,H Noda,A Shimizu,Y Shibata,T Yamada,T Kondo,Y Yoshida,Y Inden,T Murohara,

For similar circulatory and respiratory physiology: cardiovascular physiology: cardiovascular physiologic processes: myocardial contraction: systole research abstracts see: circulatory and respiratory physiology: cardiovascular physiology: cardiovascular physiologic processes: myocardial contraction: systole research

PUBMED ID PMID:

MEDLINE DATE:

Diagnostic usefulness of postexercise systolic blood pressure response for detection of coronary artery disease in patients with echocardiographic left ventricular hypertrophy. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: The Canadian journal of cardiology

VOLUME: 20

Page Numbers: 705-11

Journal Abbreviation:

ISSN: 1916-7075

DAY: 15

MONTH: May

YEAR: 2004

Diagnostic usefulness of postexercise systolic blood pressure response for detection of coronary artery disease in patients with echocardiographic left ventricular hypertrophy. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8510280

Diagnostic usefulness of postexercise systolic blood pressure response for detection of coronary artery disease in patients with echocardiographic left ventricular hypertrophy. Keywords Mesh Terms:

KEYWORDS: Systole

MESH TERMS: physiology

Chemical & Substance for Abstract: Diagnostic usefulness of postexercise systolic blood pressure response for detection of coronary artery disease in patients with echocardiographic left ventricular hypertrophy. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Diagnostic usefulness of postexercise systolic blood pressure response for detection of coronary artery disease in patients with echocardiographic left ventricular hypertrophy.

AFFILIATION: Department of Cardiology, Nagoya University Graduate School of Medicine, Japan.

Country: Canada

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Can J Cardiol

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Diagnostic usefulness of postexercise systolic blood pressure response for detection of coronary artery disease in patients with echocardiographic left ventricular hypertrophy Related Publications

• Acute and chronic effects of cardiac resynchronization in patients developing heart failure with long-term pacemaker therapy for acquired complete atrioventricular block.
• Bigeminal pulmonary vein ectopy suppressed by pulmonary vein isolation.
• Cilostazol improves long-term patency after percutaneous transluminal angioplasty in hemodialysis patients with peripheral artery disease.
• Circulating adiponectin levels in patients with atrial fibrillation.
• Circulating homocysteine levels in patients with radiofrequency catheter ablation for atrial fibrillation.
• Diagnostic usefulness of postexercise systolic blood pressure response for detection of coronary artery disease in patients with echocardiographic left ventricular hypertrophy.
• Endothelial nitric oxide synthase and methylenetetrahydrofolate reductase gene polymorphisms are associated with endothelial dysfunction in young, healthy men.
• Nifedipine improves endothelial function: role of endothelial progenitor cells.
• Pioglitazone, a peroxisome proliferator-activated receptor-gamma activator, attenuates atrial fibrosis and atrial fibrillation promotion in rabbits with congestive heart failure.
• Plasma brain natriuretic peptide level after hybrid therapy with pulmonary vein isolation and antiarrhythmic drugs for atrial fibrillation.
• Plasma brain natriuretic peptide level after radiofrequency catheter ablation of paroxysmal, persistent, and permanent atrial fibrillation.
• Prostacyclin synthase gene transfer inhibits neointimal formation by suppressing PPAR delta expression.
• Pulmonary vein antrum not always coaxial to the pulmonary vein: a dimensional pitfall to the circumferential isolation technique.
• Role of Bradykinin, Nitric Oxide, and Angiotensin II Type 2 Receptor in Imidapril-Induced Angiogenesis.
• Sirolimus-Eluting Stents vs Bare Metal Stents for Coronary Intervention in Japanese Patients With Renal Failure on Hemodialysis.
• The correlation between lipid volume in the target lesion, measured by integrated backscatter intravascular ultrasound, and post-procedural myocardial infarction in patients with elective stent implantation.
• To the editor-response.
• Usefulness of adiponectin to predict myocardial salvage following successful reperfusion in patients with acute myocardial infarction.