Diagnostic accuracy of thin-section CT and chest radiography of pediatric interstitial lung disease.

Diagnostic accuracy of thin-section CT and chest radiography of pediatric interstitial lung disease. Research Abstract Details 

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Diagnostic accuracy of thin-section CT and chest radiography of pediatric interstitial lung disease. Abstract Text:

S J Copley,M Coren,A G Nicholson,M B Rubens,A Bush,D M Hansell,

OBJECTIVE: We assessed the accuracy of thin-section CT and chest radiography to diagnose pediatric interstitial lung disease. MATERIALS AND METHODS: We identified 20 infants, boys, and girls (age range, 1 month to 14 years) with histopathologic confirmation of interstitial lung disease. Six boys and girls without interstitial lung disease were also included. Two observers independently assessed chest radiograph and CT images. The observers stated the most likely diagnosis and a differential diagnosis. We evaluated individual CT features and their distribution. RESULTS: Observers' diagnoses on CT images were correct (first choice or differential) in 66% of observations versus 45% on chest radiographs (p < 0.025). Correct diagnoses were made on first choice in 61% of CT observations versus 34% on chest radiographs (p < 0.005). Observers were confident (versus uncertain) in 42% of the CT observations versus 18% on chest radiographs; of the confident diagnoses made on CT, 91% were correct. CT interpretations were most accurate in the diagnosis of pulmonary alveolar proteinosis, congenital lymphangiectasia, and idiopathic pulmonary hemosiderosis. All healthy patients examined with CT were correctly identified as such. We noted a distinctive CT pattern in three patients with nonspecific interstitial pneumonitis and one patient with desquamative interstitial pneumonitis; the CT pattern consisted of upper zone predominant honeycombing on a background of ground-glass attenuation. CONCLUSION: A higher proportion of pediatric interstitial lung diseases can be diagnosed on thin-section CT than on chest radiographs. In our study, confident and correct diagnoses were made more frequently with CT than with chest radiographs.

Diagnostic accuracy of thin-section CT and chest radiography of pediatric interstitial lung disease. Publishing Authors By Initials

SJ Copley,M Coren,AG Nicholson,MB Rubens,A Bush,DM Hansell,

For similar tomography, x-ray computed research abstracts see: tomography, x-ray computed research

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Diagnostic accuracy of thin-section CT and chest radiography of pediatric interstitial lung disease. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: AJR. American journal of roentgenology

VOLUME: 174

Page Numbers: 549-54

Journal Abbreviation:

ISSN: 0361-803X

DAY: 15

MONTH: Feb

YEAR: 2000

Diagnostic accuracy of thin-section CT and chest radiography of pediatric interstitial lung disease. Information

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LANGUAGE: eng

NlmUniqueID: 7708173

Diagnostic accuracy of thin-section CT and chest radiography of pediatric interstitial lung disease. Keywords Mesh Terms:

KEYWORDS: Tomography, X-Ray Computed

MESH TERMS: radiography

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Grant and Affiliation Information for Diagnostic accuracy of thin-section CT and chest radiography of pediatric interstitial lung disease.

AFFILIATION: Department of Radiology, Royal Brompton Hospital, London, United Kingdom.

Country: UNITED STATES

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MEDLINETA: AJR Am J Roentgenol

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