Diagnosis and treatment of obscure GI bleeding at double balloon endoscopy.

Diagnosis and treatment of obscure GI bleeding at double balloon endoscopy. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Diagnosis and treatment of obscure GI bleeding at double balloon endoscopy. Abstract Text:

Naoki Ohmiya,Tomonori Yano,Hironori Yamamoto,Daigo Arakawa,Masanao Nakamura,Wataru Honda,Akihiro Itoh,Yoshiki Hirooka,Yasumasa Niwa,Osamu Maeda,Takafumi Ando,Tsuneyoshi Yao,Toshiyuki Matsui,Mitsuo Iida,Shinji Tanaka,Tsutomu Chiba,Choitsu Sakamoto,Kentaro Sugano,Hidemi Goto,Naoki Ohmiya,Tomonori Yano,Hironori Yamamoto,Daigo Arakawa,Masanao Nakamura,Wataru Honda,Akihiro Itoh,Yoshiki Hirooka,Yasumasa Niwa,Osamu Maeda,Takafumi Ando,Tsuneyoshi Yao,Toshiyuki Matsui,Mitsuo Iida,Shinji Tanaka,Tsutomu Chiba,Choitsu Sakamoto,Kentaro Sugano,Hidemi Goto,

BACKGROUND: Double balloon endoscopy (DBE) and videocapsule endoscopy (VCE) have been useful in managing obscure GI bleeding (OGIB). OBJECTIVE: This study evaluated the usefulness of DBE for diagnosis, treatment, and prognosis of OGIB and compared diagnostic yield between DBE and VCE in Japan. METHODS: Detection rates of abnormalities and diagnostic yields between VCE and DBE were compared in 74 patients at 5 centers. Of 244 patients who underwent DBE at Nagoya University Hospital, 130 (53%) with OGIB were enrolled for investigation of therapeutic procedures. SETTING: Seven Japanese medical centers. PATIENTS: Of 1034 patients who underwent DBE between September 2000 and December 2005 at 7 medical centers, 479 (46%) with OGIB were enrolled. RESULTS: Overall diagnostic yield of DBE for OGIB was 277 of 479 (58%). In patients with overt-ongoing bleeding, overt-previous bleeding of sporadic type, overt-previous bleeding of first attack only, occult bleeding with continuous positive fecal occult blood test (FOBT), or occult bleeding with 1 positive FOBT with iron deficiency anemia, diagnostic yield was 24 of 31 (77%), 179 of 310 (58%), 34 of 72 (47%), 24 of 35 (71%), and 56 of 93 (60%), respectively. Regarding positive findings in 277 patients, ulcers or erosions (53%) were the most frequent, followed by angiodysplasia (23%), tumors or polyps (22%), and diverticula (4%). Diagnoses in these patients were as follows: chronic inflammatory diseases (24%), vascular diseases (24%), tumor or polyps (21%), drug or radiation injury (7%), other small-bowel diseases (7%), upper GI diseases (9%), colorectal diseases (9%), and biliary disease (0.4%). Small-bowel diseases were confirmed in 226 patients (47%). Comparison of overall detection rate of abnormalities in the small bowel between VCE (65%) and DBE (53%) was not significantly different, nor was that of overall diagnostic yield between VCE (50%) and DBE (53%). Eight acute pancreatitis and 4 perforation episodes occurred with no mortalities at DBE. Of 130 patients at Nagoya University Hospital, 78 (60%) were diagnosed with small-bowel diseases and underwent treatments as follows: medication or observation only (n = 30), enteroscopic therapies (electrocoagulation in 21, clipping in 4, and polypectomy in 3), and surgery (n = 22). Small-bowel vascular diseases were more prone to rebleeding than small-bowel nonvascular diseases in patients without surgical treatment at a median follow-up of 423 days. CONCLUSIONS: DBE was relatively safe and useful for diagnosis and treatment of OGIB. A spectrum of small-bowel diseases presenting with OGIB in Japan may be distinct from that in the Western world.

Diagnosis and treatment of obscure GI bleeding at double balloon endoscopy. Publishing Authors By Initials

N Ohmiya,T Yano,H Yamamoto,D Arakawa,M Nakamura,W Honda,A Itoh,Y Hirooka,Y Niwa,O Maeda,T Ando,T Yao,T Matsui,M Iida,S Tanaka,T Chiba,C Sakamoto,K Sugano,H Goto,N Ohmiya,T Yano,H Yamamoto,D Arakawa,M Nakamura,W Honda,A Itoh,Y Hirooka,Y Niwa,O Maeda,T Ando,T Yao,T Matsui,M Iida,S Tanaka,T Chiba,C Sakamoto,K Sugano,H Goto,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Diagnosis and treatment of obscure GI bleeding at double balloon endoscopy. Journal Published:

PUBLICATION TYPE: Multicenter Study

Journal: Gastrointestinal endoscopy

VOLUME: 66

Page Numbers: S72-7

Journal Abbreviation: Gastrointest. Endosc.

ISSN: 0016-5107

DAY: 21

MONTH: Sep

YEAR: 2007

Diagnosis and treatment of obscure GI bleeding at double balloon endoscopy. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 10505

Diagnosis and treatment of obscure GI bleeding at double balloon endoscopy. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Diagnosis and treatment of obscure GI bleeding at double balloon endoscopy. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Diagnosis and treatment of obscure GI bleeding at double balloon endoscopy.

AFFILIATION: Department of Gastroenterology, Nagoya University Graduate School of Medicine, Japan.

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Gastrointest Endosc

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Diagnosis and treatment of obscure GI bleeding at double balloon endoscopy Related Publications

• A grazing-incidence reflectometer for BL-39XU at SPring-8.
• Calixarene-assisted protein refolding via liquid-liquid extraction.
• Changes in biochemical parameters related to atherosclerosis after Helicobacter pylori eradication.
• Changes in circulating cytokine levels and lymphocyte subsets in healthy liver donors after partial hepatectomy.
• Characterization of an orbital melanoma and mucosa associated lymphoid tissue (MALT) lymphoma by dual phase N-isopropyl-p-I-123 iodoamphetamine.
• Comparison of rat mandible bone characteristics in f344 substrains, f344/du and f344/n.
• Detailed simulation of the response function of an Si(Li) detector.
• Diagnosis and treatment of obscure GI bleeding at double balloon endoscopy.
• Doping-dedoping-driven optic effect of pi-conjugated polymers prepared in cholesteric-liquid-crystal electrolytes.
• Early detection and successful treatment of cerebral venous thrombosis associated with minimal change nephrotic syndrome.
• Efficacy of antiviral therapy with lamivudine after initial treatment for hepatitis B virus-related hepatocellular carcinoma.
• Enhancement of nucleopolyhedrovirus infectivity against Mamestra brassicae (Lepidoptera: Noctuidae) by proteins derived from granulovirus and a fluorescent brightener.
• Evaluation of the Airway Scope, a new video laryngoscope, in tracheal intubation by naive operators: a manikin study.
• Gastric GIST malignancy evaluated by 18FDG-PET as compared with EUS-FNA and endoscopic biopsy.
• Heat-induced conversion of beta(2)-microglobulin and hen egg-white lysozyme into amyloid fibrils.
• Hepatic epithelioid hemangioendothelioma.
• High-resolution crystal structure of beta2-microglobulin formed at pH 7.0.
• Infliximab regulates lamina propria T lymphocytes in patients with Crohn's disease.
• Leishmania (Leishmania) chagasi-infected mice as a model for the study of glomerular lesions in visceral leishmaniasis.
• Morphometric comparison of the rat mandible in f344 substrains, f344/du and f344/n.
• Phylogenetic and taxonomic relationships of northern Far Eastern phoxinin minnows, Phoxinus and Rhynchocypris (Pisces, Cyprinidae), as inferred from allozyme and mitochondrial 16S rRNA sequence analyses.
• Poly(ethylene glycol)-lipase complexes catalytically active in fluorous solvents.
• Polycyclic aromatic hydrocarbon generation behavior in the process of carbonization of wood.
• Prevalence and prognosis of gastric cancer detected by screening in a large Japanese population: data from a single institute over 30 years.
• Simultaneous quantification of seven prostanoids using liquid chromatography/tandem mass spectrometry: the effects of arachidonic acid on prostanoid production in mouse bone marrow-derived mast cells.
• Structural alterations in outer arms of IgG oligosaccharides in patients with Werner syndrome.
• Supercritical methanol for polyethylene terephthalate depolymerization: observation using simulator.
• [In Process Citation]
• [Right ventricular infarction]
• [Rise of amyloid structural biology]