Diagnosing cysts with correlation coefficient images from 2-dimensional freehand elastography.

Diagnosing cysts with correlation coefficient images from 2-dimensional freehand elastography. Research Abstract Details 

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Diagnosing cysts with correlation coefficient images from 2-dimensional freehand elastography. Abstract Text:

Rebecca C Booi,Paul L Carson,Matthew O'Donnell,Michael S Richards,Jonathan M Rubin,

OBJECTIVE: We compared the diagnostic potential of using correlation coefficient images versus elastograms from 2-dimensional (2D) freehand elastography to characterize breast cysts. METHODS: In this preliminary study, which was approved by the Institutional Review Board and compliant with the Health Insurance Portability and Accountability Act, we imaged 4 consecutive human subjects (4 cysts, 1 biopsy-verified benign breast parenchyma) with freehand 2D elastography. Data were processed offline with conventional 2D phase-sensitive speckle-tracking algorithms. The correlation coefficient in the cyst and surrounding tissue was calculated, and appearances of the cysts in the correlation coefficient images and elastograms were compared. RESULTS: The correlation coefficient in the cysts was considerably lower (14%-37%) than in the surrounding tissue because of the lack of sufficient speckle in the cysts, as well as the prominence of random noise, reverberations, and clutter, which decorrelated quickly. Thus, the cysts were visible in all correlation coefficient images. In contrast, the elastograms associated with these cysts each had different elastographic patterns. The solid mass in this study did not have the same high decorrelation rate as the cysts, having a correlation coefficient only 2.1% lower than that of surrounding tissue. CONCLUSIONS: Correlation coefficient images may produce a more direct, reliable, and consistent method for characterizing cysts than elastograms.

Diagnosing cysts with correlation coefficient images from 2-dimensional freehand elastography. Publishing Authors By Initials

RC Booi,PL Carson,M O'Donnell,MS Richards,JM Rubin,

For similar diagnosis: diagnostic techniques and procedures: diagnostic imaging: ultrasonography: ultrasonography, mammary research abstracts see: diagnosis: diagnostic techniques and procedures: diagnostic imaging: ultrasonography: ultrasonography, mammary research

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Diagnosing cysts with correlation coefficient images from 2-dimensional freehand elastography. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of ultrasound in medicine : official journ

VOLUME: 26

Page Numbers: 1201-7

Journal Abbreviation:

ISSN: 0278-4297

DAY: 20

MONTH: Sep

YEAR: 2007

Diagnosing cysts with correlation coefficient images from 2-dimensional freehand elastography. Information

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LANGUAGE: eng

NlmUniqueID: 8211547

Diagnosing cysts with correlation coefficient images from 2-dimensional freehand elastography. Keywords Mesh Terms:

KEYWORDS: Ultrasonography, Mammary

MESH TERMS: methods

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Grant and Affiliation Information for Diagnosing cysts with correlation coefficient images from 2-dimensional freehand elastography.

AFFILIATION: Department of Radiology, University of Michigan, 1500 E Medical Center Dr, Ann Arbor, MI 48109-0553 USA.

Country: United States

AGENCY: United States NCI

GRANT: R21-CA109440

ACRONYM: CA

MEDLINETA: J Ultrasound Med

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