Diabetic neuropathy is closely associated with arterial stiffening and thickness in Type 2 diabetes.

Diabetic neuropathy is closely associated with arterial stiffening and thickness in Type 2 diabetes. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Diabetic neuropathy is closely associated with arterial stiffening and thickness in Type 2 diabetes. Abstract Text:

H Yokoyama,Y Yokota,J Tada,S Kanno,H Yokoyama,Y Yokota,J Tada,S Kanno,

Aims Interaction of vascular and metabolic factors appears to contribute to the pathogenesis of diabetic neuropathy. The aim of the study was to assess the impact of arterial stiffening and thickness on diabetic neuropathy in Type 2 diabetes. Methods In 294 patients with Type 2 diabetes, neuropathy was assessed by four components: the presence of neuropathic symptoms, the absence of ankle tendon reflexes, perception of vibration scores and heart rate variation. We measured intima-media thickness (IMT) of carotid arteries to assess arterial thickening, and brachial-ankle pulse-wave velocity (PWV) and brachial pulse pressure (PP) which reflect arterial stiffening. Results Diabetic neuropathy, defined as >/= two of the four components, was significantly associated with age, duration, glycated haemoglobin (HbA(1c)), systolic blood pressure, diastolic blood pressure, PP, hypertension, retinopathy, urinary albumin excretion rate, nephropathy stages, PWV and IMT. PWV and PP were significantly associated with neuropathy independent of conventional cardiovascular risk factors. Multiple logistic regression analysis revealed that PWV, retinopathy, age, and HbA(1c), were significant independent determinants of neuropathy. Conclusions The present cross-sectional study indicates that markers for vascular wall properties such as PWV, IMT and PP are significantly associated with diabetic neuropathy. PWV and PP are significant determinants of neuropathy independent of conventional cardiovascular risk factors. Multifactorial intervention to inhibit progression of the atherosclerotic process may slow progression of neuropathy.

Diabetic neuropathy is closely associated with arterial stiffening and thickness in Type 2 diabetes. Publishing Authors By Initials

H Yokoyama,Y Yokota,J Tada,S Kanno,H Yokoyama,Y Yokota,J Tada,S Kanno,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Diabetic neuropathy is closely associated with arterial stiffening and thickness in Type 2 diabetes. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Diabetic medicine : a journal of the British Diabe

VOLUME: 24

Page Numbers: 1329-35

Journal Abbreviation: Diabet. Med.

ISSN: 0742-3071

DAY: 17

MONTH: 10

YEAR: 2007

Diabetic neuropathy is closely associated with arterial stiffening and thickness in Type 2 diabetes. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8500858

Diabetic neuropathy is closely associated with arterial stiffening and thickness in Type 2 diabetes. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Diabetic neuropathy is closely associated with arterial stiffening and thickness in Type 2 diabetes. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Diabetic neuropathy is closely associated with arterial stiffening and thickness in Type 2 diabetes.

AFFILIATION: Jiyugaoka Medical Clinic, Internal Medicine, Obihiro, Japan.

Country: England

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Diabet Med

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Diabetic neuropathy is closely associated with arterial stiffening and thickness in Type 2 diabetes Related Publications

• 1-Chloro-4,5,6,7-tetraalkyldihydroindene formation by reaction of bis(cyclopentadienyl)titanacyclopentadienes with titanium chloride.
• A case of pancreatic ascites successfully treated with endoscopic pancreatic drainage.
• A classification of unruptured middle cerebral artery bifurcation aneurysms that can help in choice of clipping technique.
• A convenient method for regional monoamine oxidase-A determination by [14C]clorgyline autoradiography.
• Apparent diffusion time of oxygen from blood to tissue in rat cerebral cortex: implication for tissue oxygen dynamics during brain functions.
• Cerebral glucose metabolic change after high-dose methotrexate treatment in patients with acute lymphocytic leukemia.
• Cycloalkanediamine derivatives as novel blood coagulation factor Xa inhibitors.
• Diabetic neuropathy is closely associated with arterial stiffening and thickness in Type 2 diabetes.
• Doppler ultrasound measurements of knee joint synovitis in rheumatoid arthritis patients treated with infliximab.
• Epigenetic regulator polycomb group protein complexes control cell fate and cancer.
• Erythematosquamous skin lesions in hereditary lactate dehydrogenase M-subunit deficiency.
• Evaluating glycogen signal contamination in muscle by (13)C MRS of the liver.
• Experimental studies on the effects of nitromin upon tumor growth, with special respect to inhibition of metastasis production.
• Follow-up examination of tuberculin allergy for seven years after vaccination with large doses of BCG in human axillary cavity.
• Formation of linear tetramers of diarylalkynes by the Zr/Cr system.
• Galantamine and carbon monoxide protect brain microvascular endothelial cells by heme oxygenase-1 induction.
• Genomic and phylogenetic analysis of two novel bovine papillomaviruses, BPV-9 and BPV-10.
• Induction of mesothelioma in p53+/- mouse by intraperitoneal application of multi-wall carbon nanotube.
• Isolation of 6,13-dipropylpentacene and its tautomerization.
• Regional cerebral blood flow and metabolism in patients with chronic obstructive carotid disease.
• Remodeling of gap junctions in ischemic and nonischemic forms of heart disease.
• Short- and long-term prognosis of blood pressure and kidney disease in women with a past history of preeclampsia.
• Suppression of cholesterol synthesis in rat liver by dihydrocholesterol administration.
• Therapeutic efficacy of basic fibroblast growth factor on experimental focal ischemia studied by magnetic resonance imaging.
• Thymocyte Proliferation Induced by Pre-T Cell Receptor Signaling Is Maintained through Polycomb Gene Product Bmi-1-Mediated Cdkn2a Repression.
• [A prosthetic ring annuloplasty with edge-to-edge repair for a treatment of severe tricuspid regurgitation]
• [A survey on nurses' caloric consumption by walking]
• [Critical role of phosphatidylserine in hemolysis due to red blood cell enzyme/membrane defects]
• [Dietary recommendations for chronic kidney disease, 2007]
• [Stranger & Danger hypothesis and allergic disease]