Dexrazoxane for anthracycline extravasation.

Dexrazoxane for anthracycline extravasation. Research Abstract Details 

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Dexrazoxane for anthracycline extravasation. Abstract Text:

Seppo W Langer,Seppo W Langer,Seppo W Langer,

Accidental extravasation of anthracycline-containing anticancer chemotherapy is a feared complication that may lead to progressive tissue damage. The condition may require extensive surgical intervention and often has severe long-term effects. Until a short while ago, there has been no effective treatment against the devastating effect of extravasated anthracycline. However, dexrazoxane has proven highly effective in preventing necrosis in both preclinical and clinical studies and is now approved in Europe (Savenetrade mark), and has orphan drug status in the USA (Totecttrade mark) for this indication. Hence, it is the first and only proven effective antidote against anthracycline extravasation injuries.

Dexrazoxane for anthracycline extravasation. Publishing Authors By Initials

SW Langer,SW Langer,SW Langer,

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Dexrazoxane for anthracycline extravasation. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Expert review of anticancer therapy

VOLUME: 7

Page Numbers: 1081-8

Journal Abbreviation: Expert Rev Anticancer Ther

ISSN: 1744-8328

DAY: 21

MONTH: Aug

YEAR: 2007

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LANGUAGE: eng

NlmUniqueID: 101123358

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AFFILIATION: Chief Medical Oncologist, Copenhagen University Hospital, Rigshospitalet, Department of Oncology, Section 5073, Blegdamsvej 9, DK-2100 Copenhagen, Denmark. seppo.langer@rh.regionh.dk.

Country: England

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MEDLINETA: Expert Rev Anticancer Ther

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