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Dexamethasone suppression in essential hypertension: effects on cortisol and blood pressure.

Dexamethasone suppression in essential hypertension: effects on cortisol and blood pressure. Research Abstract Details 

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  • Dexamethasone suppression in essential hypertension: effects on cortisol and blood pressure. Abstract Text:

    j a whitworthJ A Whitworth,d gordonD Gordon,n mclachlan-troupN McLachlan-Troup,b a scogginsB A Scoggins,r w mouldsR W Moulds,

    Hypothalamic-pituitary-adrenal axis (HPA) function was examined in normotensive (n = 20) and hypertensive (n = 16) men, by measurement of basal cortisol levels, diurnal variation and the response to dexamethasone suppression. Comparison between groups did not reveal any differences in basal cortisol concentrations, in their diurnal variation, or in response to dexamethasone suppression. In separate studies, treatment with dexamethasone did not alter blood pressure in normal men (n = 6) but produced a small fall in pressure in hypertensive subjects (n = 8), compatible with the notion that the HPA might contribute to blood pressure elevation in some subjects with essential hypertension.

    Dexamethasone suppression in essential hypertension: effects on cortisol and blood pressure. Publishing Authors By Initials

    ja whitworthJA Whitworth,d gordonD Gordon,n mclachlan-troupN McLachlan-Troup,ba scogginsBA Scoggins,rw mouldsRW Moulds,

    For similar endocrine system: endocrine glands: pituitary-adrenal system research abstracts see: endocrine system: endocrine glands: pituitary-adrenal system research

    PUBMED ID PMID:

    MEDLINE DATE:

    Dexamethasone suppression in essential hypertension: effects on cortisol and blood pressure. Journal Published:

    PUBLICATION TYPE: Research Support, Non-U.S. Gov

    Journal: Clinical and experimental hypertension. Part A, Th

    VOLUME: 11

    Page Numbers: 323-35

    Journal Abbreviation:

    ISSN: 0730-0077

    DAY: 12

    MONTH: 02

    YEAR: 1989

    Dexamethasone suppression in essential hypertension: effects on cortisol and blood pressure. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 8207790

    Dexamethasone suppression in essential hypertension: effects on cortisol and blood pressure. Keywords Mesh Terms:

    KEYWORDS: Pituitary-Adrenal System

    MESH TERMS: physiopathology

    Chemical & Substance for Abstract: Dexamethasone suppression in essential hypertension: effects on cortisol and blood pressure. Information

    Substance Name: Hydrocortisone

    Registry Number: 50-23-7

    Grant and Affiliation Information for Dexamethasone suppression in essential hypertension: effects on cortisol and blood pressure.

    AFFILIATION: Department of Nephrology, Royal Melbourne Hospital, Parkville, Australia.

    Country: UNITED STATES

    UNITED STATES Research PublicationUNITED STATES Research Publication

    AGENCY:

    GRANT:

    ACRONYM:

    MEDLINETA: Clin Exp Hypertens A

    REFSOURCE:

    DATABASENAME:

    ACCESSION NUMBER:

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