Determination of the surface energy distributions of different processed lactose.

Determination of the surface energy distributions of different processed lactose. Research Abstract Details 

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Determination of the surface energy distributions of different processed lactose. Abstract Text:

Frank Thielmann,Daniel J Burnett,Jerry Y Y Heng,Frank Thielmann,Daniel J Burnett,Jerry Y Y Heng,Frank Thielmann,Daniel J Burnett,Jerry Y Y Heng,

Particulate interactions between drug and lactose carrier in dry powder inhaler formulations are affected by the heterogenous energy distribution on the surface of the individual compounds. A new method based on Inverse Gas Chromatography at finite concentration is applied to study the energy heterogeneity of untreated, milled, and recrystallized lactose of similar particle size distribution. Energy distributions for the dispersive surface energy and the specific free energy of ethanol are obtained. Milling causes an increase in surface energy due to formation of amorphous regions. Untreated and recrystallized materials have similar surface energies at low surface coverages but show clear differences in energy distribution.

Determination of the surface energy distributions of different processed lactose. Publishing Authors By Initials

F Thielmann,DJ Burnett,JY Heng,F Thielmann,DJ Burnett,JY Heng,F Thielmann,DJ Burnett,JY Heng,

For similar investigative techniques: technology, pharmaceutical research abstracts see: investigative techniques: technology, pharmaceutical research

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Determination of the surface energy distributions of different processed lactose. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Drug development and industrial pharmacy

VOLUME: 33

Page Numbers: 1240-53

Journal Abbreviation:

ISSN: 0363-9045

DAY: 21

MONTH: Nov

YEAR: 2007

Determination of the surface energy distributions of different processed lactose. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7802620

Determination of the surface energy distributions of different processed lactose. Keywords Mesh Terms:

KEYWORDS: Technology, Pharmaceutical

MESH TERMS: chemistry

Chemical & Substance for Abstract: Determination of the surface energy distributions of different processed lactose. Information

Substance Name: Lactose

Registry Number: 63-42-3

Grant and Affiliation Information for Determination of the surface energy distributions of different processed lactose.

AFFILIATION: Surface Measurement Systems UK, London, UK. frank_thielmann@yahoo.co.uk

Country: United States

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MEDLINETA: Drug Dev Ind Pharm

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