Determination of tetrodotoxin and its analogs in the puffer fish Takifugu oblongus from Bangladesh by hydrophilic interaction chromatography and mass-spectrometric detection.

Determination of tetrodotoxin and its analogs in the puffer fish Takifugu oblongus from Bangladesh by hydrophilic interaction chromatography and mass-spectrometric detection. Research Abstract Details 

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Determination of tetrodotoxin and its analogs in the puffer fish Takifugu oblongus from Bangladesh by hydrophilic interaction chromatography and mass-spectrometric detection. Abstract Text:

Marc Diener,Bernd Christian,M Sagir Ahmed,Bernd Luckas,Marc Diener,Bernd Christian,M Sagir Ahmed,Bernd Luckas,Marc Diener,Bernd Christian,M Sagir Ahmed,Bernd Luckas,

Tetrodotoxin (TTX) and its analogs (TTXs), widely distributed among marine as well as terrestrial animals, induce dangerous intoxications. These highly potential toxins are also known as the causative agent of puffer fish poisoning. A newly developed highly sensitive method for determination of TTXs based on hydrophilic interaction chromatography and mass-spectrometric detection is presented. TTX, anhydrotetrodotoxin, 11-deoxytetrodotoxin and trideoxytetrodotoxin were determined in separated tissues of Bangladeshi marine puffers, Takifugu oblongus. TTX was predominant in skin, muscle and liver, whereas trideoxytetrodotoxin preponderated in the ovary. The toxicity of the various tissues was determined by a mouse bioassay.

Determination of tetrodotoxin and its analogs in the puffer fish Takifugu oblongus from Bangladesh by hydrophilic interaction chromatography and mass-spectrometric detection. Publishing Authors By Initials

M Diener,B Christian,MS Ahmed,B Luckas,M Diener,B Christian,MS Ahmed,B Luckas,M Diener,B Christian,MS Ahmed,B Luckas,

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Determination of tetrodotoxin and its analogs in the puffer fish Takifugu oblongus from Bangladesh by hydrophilic interaction chromatography and mass-spectrometric detection. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Analytical and bioanalytical chemistry

VOLUME: 389

Page Numbers: 1997-2002

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ISSN: 1618-2642

DAY: 27

MONTH: 09

YEAR: 2007

Determination of tetrodotoxin and its analogs in the puffer fish Takifugu oblongus from Bangladesh by hydrophilic interaction chromatography and mass-spectrometric detection. Information

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LANGUAGE: eng

NlmUniqueID: 101134327

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AFFILIATION: Institute of Nutrition, University of Jena, Dornburger Street 25, 07743 Jena, Germany. marc.diener@uni-jena.de

Country: Germany

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MEDLINETA: Anal Bioanal Chem

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