Determination of interbilayer and transbilayer lipid transfers by time-resolved small-angle neutron scattering.

Determination of interbilayer and transbilayer lipid transfers by time-resolved small-angle neutron scattering. Research Abstract Details 

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Determination of interbilayer and transbilayer lipid transfers by time-resolved small-angle neutron scattering. Abstract Text:

Minoru Nakano,Masakazu Fukuda,Takayuki Kudo,Hitoshi Endo,Tetsurou Handa,Minoru Nakano,Masakazu Fukuda,Takayuki Kudo,Hitoshi Endo,Tetsurou Handa,

We applied a time-resolved small-angle neutron scattering technique to the vesicle system of dimyristoylphosphatidylcholine for the first time to determine lipid kinetics. The observed kinetics could be explicitly represented by a simple model that includes two independent kinetic parameters, i.e., the rates of transbilayer and interbilayer exchange. This technique is perfectly suited for the determination of lipid exchange kinetics in equilibrium and applicable to evaluation of the activity of the factors relevant to lipid migration, such as translocase and lipid transfer proteins.

Determination of interbilayer and transbilayer lipid transfers by time-resolved small-angle neutron scattering. Publishing Authors By Initials

M Nakano,M Fukuda,T Kudo,H Endo,T Handa,M Nakano,M Fukuda,T Kudo,H Endo,T Handa,

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Determination of interbilayer and transbilayer lipid transfers by time-resolved small-angle neutron scattering. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Physical review letters

VOLUME: 98

Page Numbers: 238101

Journal Abbreviation: Phys. Rev. Lett.

ISSN: 0031-9007

DAY: 7

MONTH: 06

YEAR: 2007

Determination of interbilayer and transbilayer lipid transfers by time-resolved small-angle neutron scattering. Information

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LANGUAGE: eng

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AFFILIATION: Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606-8501, Japan. mnakano@pharm.kyoto-u.ac.jp

Country: United States

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MEDLINETA: Phys Rev Lett

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