Determination of carryover and contamination for mass spectrometry-based chromatographic assays.

Determination of carryover and contamination for mass spectrometry-based chromatographic assays. Research Abstract Details 

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Determination of carryover and contamination for mass spectrometry-based chromatographic assays. Abstract Text:

Nicola C Hughes,Ernest Y K Wong,Juan Fan,Navgeet Bajaj,Nicola C Hughes,Ernest Y K Wong,Juan Fan,Navgeet Bajaj,Nicola C Hughes,Ernest Y K Wong,Juan Fan,Navgeet Bajaj,

The Third American Association of Pharmaceutical Scientists/Food and Drug Administration Bioanalytical Workshop, held in 2006, reviewed and evaluated current practices and proposed that carryover and contamination be assessed not only during the validation of an assay but also during the application of the method in a study. In this article, the potential risks of carryover and contamination in each stage of a bioanalytical method are discussed, to explain to the industry why this recommendation is being made.

Determination of carryover and contamination for mass spectrometry-based chromatographic assays. Publishing Authors By Initials

NC Hughes,EY Wong,J Fan,N Bajaj,NC Hughes,EY Wong,J Fan,N Bajaj,NC Hughes,EY Wong,J Fan,N Bajaj,

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Determination of carryover and contamination for mass spectrometry-based chromatographic assays. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: The AAPS journal

VOLUME: 9

Page Numbers: E353-60

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ISSN: 1550-7416

DAY: 2

MONTH: 11

YEAR: 2007

Determination of carryover and contamination for mass spectrometry-based chromatographic assays. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Determination of carryover and contamination for mass spectrometry-based chromatographic assays.

AFFILIATION: Biovail Contract Research, Toronto, ON M1L 4S4. Nicki.Hughes@biovail.com

Country: United States

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MEDLINETA: AAPS J

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