Determination of aluminium content in aluminium hydroxide formulation by FT-NIR transmittance spectroscopy.

Determination of aluminium content in aluminium hydroxide formulation by FT-NIR transmittance spectroscopy. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Determination of aluminium content in aluminium hydroxide formulation by FT-NIR transmittance spectroscopy. Abstract Text:

Xuxin Lai,Yiwu Zheng,Ib ,Henrik Josephsen,Henning , Larsen,Henrik Ipsen,Susanne Jacobsen,Xuxin Lai,Yiwu Zheng,Ib Søndergaard,Henrik Josephsen,Henning Løwenstein,Jørgen Nedergaard Larsen,Henrik Ipsen,Susanne Jacobsen,Xuxin Lai,Yiwu Zheng,Ib Søndergaard,Henrik Josephsen,Henning Løwenstein,Jørgen Nedergaard Larsen,Henrik Ipsen,Susanne Jacobsen,

A method for determining the aluminium content of an aluminium hydroxide suspension using near infrared (NIR) transmittance spectroscopy has been developed. Inductively coupled plasma-atomic emission spectroscopy (ICP-AES) was used as reference method. The factors influencing the NIR analysis, such as different sample containers (transmission cell and cuvette), sedimentation in the suspension, day-to-day variation and batch-to-batch variation have been studied before constructing a calibration model. Seven dilutions (0-4100mgAl/L) of five batches of aluminium hydroxide suspension samples were measured by NIR transmission each on five different days, with total of 175 spectra used for the calibration set. The multivariate data analysis technique partial least square regression (PLSR) was applied to build the calibration model. Six batches of aluminium hydroxide samples were used for the test set. ICP-AES and NIR transmittance spectroscopy exhibit comparable precision and accuracy. The NIR method provides several advantages: no complicated sample preparation; easy to operate; fast and non-destructive. In conclusion, NIR transmittance spectroscopy can be an alternative analytical method for determining aluminium content in aluminium hydroxide suspension.

Determination of aluminium content in aluminium hydroxide formulation by FT-NIR transmittance spectroscopy. Publishing Authors By Initials

X Lai,Y Zheng,I ,H Josephsen,H ,JN Larsen,H Ipsen,S Jacobsen,X Lai,Y Zheng,I Søndergaard,H Josephsen,H Løwenstein,JN Larsen,H Ipsen,S Jacobsen,X Lai,Y Zheng,I Søndergaard,H Josephsen,H Løwenstein,JN Larsen,H Ipsen,S Jacobsen,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Determination of aluminium content in aluminium hydroxide formulation by FT-NIR transmittance spectroscopy. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Vaccine

VOLUME: 25

Page Numbers: 8732-40

Journal Abbreviation: Vaccine

ISSN: 0264-410X

DAY: 5

MONTH: 11

YEAR: 2007

Determination of aluminium content in aluminium hydroxide formulation by FT-NIR transmittance spectroscopy. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8406899

Determination of aluminium content in aluminium hydroxide formulation by FT-NIR transmittance spectroscopy. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Determination of aluminium content in aluminium hydroxide formulation by FT-NIR transmittance spectroscopy. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Determination of aluminium content in aluminium hydroxide formulation by FT-NIR transmittance spectroscopy.

AFFILIATION: Enzyme and Protein Chemistry Group, BioCentrum-DTU, Building 224, Søltofts Plads, Technical University of Denmark, DK-2800 Kgs. Lyngby, Denmark; ALK-Abelló A/S, Bøge Allé 6-8, DK-2970 Hørsholm, Denmark.

Country: Netherlands

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Vaccine

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Determination of aluminium content in aluminium hydroxide formulation by FT-NIR transmittance spectroscopy Related Publications

• A chiral primary amine thiourea catalyst for the highly enantioselective direct conjugate addition of alpha,alpha-disubstituted aldehydes to nitroalkenes.
• A tele-obstetric broadband service including ultrasound, videoconferencing and cardiotocogram. A high cost and a low volume of patients.
• Acute child poisonings in Oslo: a 2-year prospective study.
• Albuminuria as risk factor for initiation and progression of carotid atherosclerosis in non-diabetic persons: the Tromsø Study.
• Alpha,beta-unsaturated beta-silyl imide substrates for catalytic, enantioselective conjugate additions: a total synthesis of (+)-lactacystin and the discovery of a new proteasome inhibitor.
• Analysis of protein structures and interactions in complex food by near-infrared spectroscopy. 1. Gluten powder.
• Analysis of protein structures and interactions in complex food by near-infrared spectroscopy. 2. Hydrated gluten.
• Asymmetric catalysis of the transannular Diels-Alder reaction.
• Correlations between longitudinal changes in transitional zone volume and measures of benign prostatic hyperplasia in a population-based cohort.
• Dropout in a longitudinal, cohort study of urologic disease in community men.
• Enantioselective alkylation of acyclic alpha,alpha-disubstituted tributyltin enolates catalyzed by a {Cr(salen)} complex.
• Enhancing research on cancer survivors.
• Genetic analyses of DNA methyltransferases in Arabidopsis thaliana.
• Highly enantioselective direct conjugate addition of ketones to nitroalkenes promoted by a chiral primary amine-thiourea catalyst.
• Indium-mediated asymmetric allylation of acylhydrazones using a chiral urea catalyst.
• Long-term school outcomes for children with attention-deficit/hyperactivity disorder: a population-based perspective.
• Modifiers of long-term school outcomes for children with attention-deficit/hyperactivity disorder: does treatment with stimulant medication make a difference? Results from a population-based study.
• Prospective, longitudinal study of leisure-time exercise in women with early-stage breast cancer.
• Protective association between nonsteroidal antiinflammatory drug use and measures of benign prostatic hyperplasia.
• Quantitative amplitude and phase contrast imaging in a scanning transmission X-ray microscope.
• RNAi, DRD1, and histone methylation actively target developmentally important non-CG DNA methylation in arabidopsis.
• Reproductive performance of beef heifers: Effects of vulvo-vaginitis, Ureaplasma diversum and prebreeding antibiotic administration.
• Role of RNA polymerase IV in plant small RNA metabolism.
• Targeting of metallothionein by L-homocysteine: a novel mechanism for disruption of zinc and redox homeostasis.
• The Arabidopsis LHP1 protein colocalizes with histone H3 Lys27 trimethylation.
• The SRA methyl-cytosine-binding domain links DNA and histone methylation.
• Transumbilical approach to intraoperative enteroscopy in a child with intussusception and peutz-jeghers syndrome.
• Two-step recruitment of RNA-directed DNA methylation to tandem repeats.
• UHRF1 plays a role in maintaining DNA methylation in mammalian cells.
• Whole-genome analysis of histone H3 lysine 27 trimethylation in Arabidopsis.