Determinants of plasma homocysteine levels and carotid intima-media thickness in Japanese.

Determinants of plasma homocysteine levels and carotid intima-media thickness in Japanese. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Determinants of plasma homocysteine levels and carotid intima-media thickness in Japanese. Abstract Text:

Noboru Takamura,Yasuyo Abe,Mio Nakazato,Takahiro Maeda,Mitsuhiro Wada,Kenichiro Nakashima,Yosuke Kusano,Kiyoshi Aoyagi,Noboru Takamura,Yasuyo Abe,Mio Nakazato,Takahiro Maeda,Mitsuhiro Wada,Kenichiro Nakashima,Yosuke Kusano,Kiyoshi Aoyagi,Noboru Takamura,Yasuyo Abe,Mio Nakazato,Takahiro Maeda,Mitsuhiro Wada,Kenichiro Nakashima,Yosuke Kusano,Kiyoshi Aoyagi,

Although hyperhomocysteinemia is considered to be a key risk factor for atherosclerosis, especially in Western countries, its role in the Asian population is still controversial. In this study, we evaluated the determinants of homocysteine and carotid intima-media thickness, a clinical marker for the detection of atherosclerosis, in Japanese. In 289 Japanese adults (age 37-86 yrs), we screened plasma total homocysteine by high performance liquid chromatography and evaluated maximum carotid intima-media thickness by ultrasound. Other blood chemistry values were also measured. Total homocysteine levels were higher in men than in women and increased with age. In multiple regression analysis, adjusted for age and sex, serum creatinine was a powerful determinant of homocysteine (beta=3.3, p<0.01). Maximum carotid intima-media thickness was higher in men than in women and increased with age. When adjusted for age and sex, systolic blood pressure was independently correlated with maximum carotid intima-media thickness (beta=0.001, p<0.01). Our current results support previous findings that in addition to age and sex, serum creatinine and systolic blood pressure are independent determinants of homocysteine and carotid intima-media thickness, respectively.

Determinants of plasma homocysteine levels and carotid intima-media thickness in Japanese. Publishing Authors By Initials

N Takamura,Y Abe,M Nakazato,T Maeda,M Wada,K Nakashima,Y Kusano,K Aoyagi,N Takamura,Y Abe,M Nakazato,T Maeda,M Wada,K Nakashima,Y Kusano,K Aoyagi,N Takamura,Y Abe,M Nakazato,T Maeda,M Wada,K Nakashima,Y Kusano,K Aoyagi,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Determinants of plasma homocysteine levels and carotid intima-media thickness in Japanese. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Asia Pacific journal of clinical nutrition

VOLUME: 16

Page Numbers: 698-703

Journal Abbreviation:

ISSN: 0964-7058

DAY: 28

MONTH: 11

YEAR: 2007

Determinants of plasma homocysteine levels and carotid intima-media thickness in Japanese. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9440304

Determinants of plasma homocysteine levels and carotid intima-media thickness in Japanese. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Determinants of plasma homocysteine levels and carotid intima-media thickness in Japanese. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Determinants of plasma homocysteine levels and carotid intima-media thickness in Japanese.

AFFILIATION: Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences, 1-12-4 Sakamoto, Nagasaki 852-8523, Japan takamura@nagasaki-u.ac.jp.

Country: Australia

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Asia Pac J Clin Nutr

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Determinants of plasma homocysteine levels and carotid intima-media thickness in Japanese Related Publications

• Altered expression of TLR homolog RP105 on monocytes hypersensitive to LPS in patients with primary biliary cirrhosis.
• Antibacterial activity of peptides derived from the C-terminal region of a hemolytic lectin, CEL-III, from the marine invertebrate Cucumaria echinata.
• Aortic root replacement in behcet disease.
• Arginine vasopressin is an ideal drug after cardiac surgery for the management of low systemic vascular resistant hypotension concomitant with pulmonary hypertension.
• Bidirectional gastric differentiation in cellular mucin phenotype (foveolar and pyloric) in serrated adenoma and hyperplastic polyp of the colorectum.
• Calcium-entry blockers in the treatment of vestibular disorders.
• Characterization of recombinant CEL-I, a GalNAc-specific C-type lectin, expressed in Escherichia coli using an artificial synthetic gene.
• Characterization of the interaction of hemolytic lectin CEL-III from the marine invertebrate, Cucumaria echinata, with artificial lipid membranes: involvement of neutral sphingoglycolipids in the pore-forming process.
• Congenital kinking of aortic arch associated with thoracic aortic aneurysm.
• Determinants of plasma homocysteine levels and carotid intima-media thickness in Japanese.
• Development and evaluation of the physical activity questionnaire for elderly Japanese: the Nakanojo study.
• Early upsurge in anti-HBs titer possibly caused by the immunomodulative, not by the mutagenetic effect of interferon and ribavirin.
• Fabrication of spatial walk-off polarizing film exhibiting a large split angle by oblique silicon deposition.
• Fucosylated fraction of alpha-fetoprotein, L3, as a useful prognostic factor in patients with hepatocellular carcinoma with special reference to low concentrations of serum alpha-fetoprotein.
• High-resolution computed tomography using multiplanar reconstruction for the facial nerve canal.
• Identification of the intraparotid facial nerve on magnetic resonance imaging.
• Magnetic resonance imaging findings in a patient with bilateral facial paralysis due to malignant lymphoma.
• Real time observation of binding of herpes simplex virus type 1 (HSV-1) to Vero cells and neutralization of HSV-1 by sulfonated human immunoglobulin.
• Real time observation of the binding of herpes simplex virus type 1 (HSV-1) to immobilized heparan sulfate and the neutralization of HSV-1 by sulfonated human immunoglobulin.
• Reflection-wavelength control method for layer-by-layer controlled x-ray multilayer mirrors.
• Relationships among estrous behavior, superovulatory response and grade 1 embryo sex ratio in superovulated Holstein heifers.
• Sex, age, season, and habitual physical activity of older Japanese: the nakanojo study.
• Slow saccades and quick phases of nystagmus after pontine lesions.
• Strategy for isolated iliac artery aneurysms.
• Sudden-onset tinnitus associated with arterial dissection of the vertebrobasilar system.
• Temporal treatment with interferon-beta prevents hepatocellular carcinoma in hepatitis B virus X gene transgenic mice.
• [Acute aortic dissection complicated with acute myocardial infarction--a case report of successful operation for the case of DOA]
• [Fast-track management for conventional coronary artery bypass surgery]
• [Percutaneous tracheostomy for the management of the patient with a difficult airway]
• [Possibility of improving postoperative QOL by selecting the gastroepiploic artery as a graft in coronary artery bypass]