Detection of the level of urinary FPA in chronic nephritis with renal failure and its clinical implication.

Detection of the level of urinary FPA in chronic nephritis with renal failure and its clinical implication. Research Abstract Details 

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Detection of the level of urinary FPA in chronic nephritis with renal failure and its clinical implication. Abstract Text:

L Liu,S Song,Z Liu,W Wei,

The level of urinary FPA was assayed by high performance liquid chromatography (HPLC) in 42 normal controls, 57 cases of chronic glomerulonephritis, including 24 with normal renal function, 12 with renal insufficiency and 21 with uremia. Their levels were 24.40 +/- 10.30 micrograms/L, 26.99 +/- 5.77 micrograms/L, 38.81 +/- 6.28 micrograms/L, 79.74 +/- 18.76 micrograms/L, respectively. The level of urinary FPA in renal insufficiency function group was significantly higher than those of the control group and normal renal function group (P < 0.01). The patients with uremia presented dramatically higher level of urinary FPA than those in the renal insufficiency group (P < 0.01). A positive correlation was found between the level of urinary FPA and the blood creatine (r = 0.9120, P < 0.01). It was suggested that a hypercoagulable state existed in the patients with chronic nephritis with renal failure, in which the severity was closely related with the occurrence and development of the disease. The urinary FPA could serve as a good indicator for renal function.

Detection of the level of urinary FPA in chronic nephritis with renal failure and its clinical implication. Publishing Authors By Initials

L Liu,S Song,Z Liu,W Wei,

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Detection of the level of urinary FPA in chronic nephritis with renal failure and its clinical implication. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of Tongji Medical University = Tong ji yi

VOLUME: 19

Page Numbers: 304-6

Journal Abbreviation: J. Tongji Med. Univ.

ISSN: 0257-716X

DAY: 26

MONTH: 08

YEAR: 1999

Detection of the level of urinary FPA in chronic nephritis with renal failure and its clinical implication. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Detection of the level of urinary FPA in chronic nephritis with renal failure and its clinical implication.

AFFILIATION: Institute of Hematology, Tongji Medical University, Wuhan 430022.

Country: China

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MEDLINETA: J Tongji Med Univ

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