Detection of respiratory viruses and subtype identification of influenza A viruses by GreeneChipResp oligonucleotide microarray.

Detection of respiratory viruses and subtype identification of influenza A viruses by GreeneChipResp oligonucleotide microarray. Research Abstract Details 

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Detection of respiratory viruses and subtype identification of influenza A viruses by GreeneChipResp oligonucleotide microarray. Abstract Text:

Phenix-Lan Quan,Gustavo Palacios,Omar J Jabado,Sean Conlan,David L Hirschberg,Francisco Pozo,Philippa J M Jack,Daniel Cisterna,Neil Renwick,Jeffrey Hui,Andrew Drysdale,Rachel Amos-Ritchie,Elsa Baumeister,Vilma Savy,Kelly M Lager, Richt,David B Boyle,Adolfo ,Inmaculada Casas,Pilar ,Thomas Briese,W Ian Lipkin,

Acute respiratory infections are significant causes of morbidity, mortality, and economic burden worldwide. An accurate, early differential diagnosis may alter individual clinical management as well as facilitate the recognition of outbreaks that have implications for public health. Here we report on the establishment and validation of a comprehensive and sensitive microarray system for detection of respiratory viruses and subtyping of influenza viruses in clinical materials. Implementation of a set of influenza virus enrichment primers facilitated subtyping of influenza A viruses through the differential recognition of hemagglutinins 1 through 16 and neuraminidases 1 through 9. Twenty-one different respiratory virus species were accurately characterized, including a recently identified novel genetic clade of rhinovirus.

Detection of respiratory viruses and subtype identification of influenza A viruses by GreeneChipResp oligonucleotide microarray. Publishing Authors By Initials

PL Quan,G Palacios,OJ Jabado,S Conlan,DL Hirschberg,F Pozo,PJ Jack,D Cisterna,N Renwick,J Hui,A Drysdale,R Amos-Ritchie,E Baumeister,V Savy,KM Lager,JA Richt,DB Boyle,A ,I Casas,P ,T Briese,WI Lipkin,

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Detection of respiratory viruses and subtype identification of influenza A viruses by GreeneChipResp oligonucleotide microarray. Journal Published:

PUBLICATION TYPE: Validation Studies

Journal: Journal of clinical microbiology

VOLUME: 45

Page Numbers: 2359-64

Journal Abbreviation: J. Clin. Microbiol.

ISSN: 0095-1137

DAY: 6

MONTH: 06

YEAR: 2007

Detection of respiratory viruses and subtype identification of influenza A viruses by GreeneChipResp oligonucleotide microarray. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7505564

Detection of respiratory viruses and subtype identification of influenza A viruses by GreeneChipResp oligonucleotide microarray. Keywords Mesh Terms:

KEYWORDS: Viruses

MESH TERMS: isolation & purification

Chemical & Substance for Abstract: Detection of respiratory viruses and subtype identification of influenza A viruses by GreeneChipResp oligonucleotide microarray. Information

Substance Name: Neuraminidase

Registry Number: EC 3.2.1.18

Grant and Affiliation Information for Detection of respiratory viruses and subtype identification of influenza A viruses by GreeneChipResp oligonucleotide microarray.

AFFILIATION: Jerome L. and Dawn Greene Infectious Disease Laboratory, Mailman School of Public Health, Columbia University, 722 West 168th Street, Room 1801, New York, NY 10032, USA.

Country: United States

AGENCY: United States NIAID

GRANT: U54AI57158

ACRONYM: AI

MEDLINETA: J Clin Microbiol

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