Detection of pyramidal tract lesions in amyotrophic lateral sclerosis with magnetization-transfer measurements.

Detection of pyramidal tract lesions in amyotrophic lateral sclerosis with magnetization-transfer measurements. Research Abstract Details 

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Detection of pyramidal tract lesions in amyotrophic lateral sclerosis with magnetization-transfer measurements. Abstract Text:

Y Kato,K Matsumura,Y Kinosada,Y Narita,S Kuzuhara,T Nakagawa,

PURPOSE: To determine the presence of small lesions in the pyramidal tract in patients with amyotrophic lateral sclerosis (ALS) by using magnetization-transfer (MT) measurements and MR imaging. METHODS: MT ratios (MTRs) were measured in the posterior limb of the internal capsule in nine patients with ALS and in nine healthy volunteers. RESULTS: The mean value of MTRs (%) in patients with ALS was 15.76 +/- 1.48, while that of the control subjects was 19.83 +/- 1.54. The difference was statistically significant. CONCLUSIONS: MT measurements are useful for detecting abnormalities associated with degeneration of the pyramidal tract in patients with ALS.

Detection of pyramidal tract lesions in amyotrophic lateral sclerosis with magnetization-transfer measurements. Publishing Authors By Initials

Y Kato,K Matsumura,Y Kinosada,Y Narita,S Kuzuhara,T Nakagawa,

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Detection of pyramidal tract lesions in amyotrophic lateral sclerosis with magnetization-transfer measurements. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: AJNR. American journal of neuroradiology

VOLUME: 18

Page Numbers: 1541-7

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ISSN: 0195-6108

DAY: 14

MONTH: Sep

YEAR: 1997

Detection of pyramidal tract lesions in amyotrophic lateral sclerosis with magnetization-transfer measurements. Information

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LANGUAGE: eng

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Detection of pyramidal tract lesions in amyotrophic lateral sclerosis with magnetization-transfer measurements. Keywords Mesh Terms:

KEYWORDS: Reference Values

MESH TERMS: pathology

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Grant and Affiliation Information for Detection of pyramidal tract lesions in amyotrophic lateral sclerosis with magnetization-transfer measurements.

AFFILIATION: Department of Neurology, Mie University School of Medicine, Japan.

Country: UNITED STATES

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MEDLINETA: AJNR Am J Neuroradiol

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