Detection of hepatocellular carcinoma: comparison of low- and high-spatial-resolution dynamic MR images.

Detection of hepatocellular carcinoma: comparison of low- and high-spatial-resolution dynamic MR images. Research Abstract Details 

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Detection of hepatocellular carcinoma: comparison of low- and high-spatial-resolution dynamic MR images. Abstract Text:

M Kanematsu,H Hoshi,T Murakami,K Itoh,M Hori,H Kondo,H Nakamura,

OBJECTIVE: The purpose of our study was to compare the diagnostic performance of low- and high-spatial-resolution gadolinium chelate-enhanced triphasic dynamic gradient-recalled echo (GRE) MR images in the detection of hepatocellular carcinoma. MATERIALS AND METHODS: Triphasic dynamic MR images obtained with low (256 x 128) and high (512 x 224) image matrices in 28 patients with 65 hepatocellular carcinomas (HCCs) were retrospectively analyzed. Image review was conducted on a segment-by-segment basis; a total of 215 liver segments, including 56 segments with tumor burden, were reviewed for the presence of HCC by three independent radiologists. Detectability was evaluated with relative sensitivity, specificity, and receiver operating characteristic (ROC) analysis. Image quality was evaluated with rank order analysis. RESULTS: Relative sensitivity was statistically significantly better with high-spatial-resolution images than with low-spatial-resolution images (p < .005). Relative specificity was statistically significantly better with low-spatial-resolution images than with high-spatial-resolution images (p < .001). Diagnostic accuracy determined by ROC curve analysis was marginally higher with high-spatial-resolution (area under ROC curve [Az] = .97) than with low-spatial-resolution (Az = .94, p < .09) images. Image quality was statistically significantly better with high-spatial-resolution images (p < .005). CONCLUSION: High-spatial-resolution dynamic GRE images were superior to low-spatial-resolution images in sensitivity of detecting HCC and in image quality. Triphasic dynamic GRE imaging in the screening and follow-up programs of patients with suspected HCC should be performed using high image matrices.

Detection of hepatocellular carcinoma: comparison of low- and high-spatial-resolution dynamic MR images. Publishing Authors By Initials

M Kanematsu,H Hoshi,T Murakami,K Itoh,M Hori,H Kondo,H Nakamura,

For similar investigative techniques: epidemiologic methods: statistics as topic: sensitivity and specificity research abstracts see: investigative techniques: epidemiologic methods: statistics as topic: sensitivity and specificity research

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Detection of hepatocellular carcinoma: comparison of low- and high-spatial-resolution dynamic MR images. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: AJR. American journal of roentgenology

VOLUME: 173

Page Numbers: 1207-12

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ISSN: 0361-803X

DAY: 15

MONTH: Nov

YEAR: 1999

Detection of hepatocellular carcinoma: comparison of low- and high-spatial-resolution dynamic MR images. Information

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LANGUAGE: eng

NlmUniqueID: 7708173

Detection of hepatocellular carcinoma: comparison of low- and high-spatial-resolution dynamic MR images. Keywords Mesh Terms:

KEYWORDS: Sensitivity and Specificity

MESH TERMS: diagnosis

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Grant and Affiliation Information for Detection of hepatocellular carcinoma: comparison of low- and high-spatial-resolution dynamic MR images.

AFFILIATION: Department of Radiology, Gifu University School of Medicine, Japan.

Country: UNITED STATES

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MEDLINETA: AJR Am J Roentgenol

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