Detection of four adenovirus serotypes within water-isolated strains of Acanthamoeba in the Canary Islands, Spain.

Detection of four adenovirus serotypes within water-isolated strains of Acanthamoeba in the Canary Islands, Spain. Research Abstract Details 

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Detection of four adenovirus serotypes within water-isolated strains of Acanthamoeba in the Canary Islands, Spain. Abstract Text:

Jacob Lorenzo-Morales,Nieves Coronado-Alvarez,Enrique ,Sutherland K Maciver,Basilio Valladares,Jacob Lorenzo-Morales,Nieves Coronado-Alvarez,Enrique ,Sutherland K Maciver,Basilio Valladares,

We surveyed 236 potentially pathogenic Acanthamoeba strains, isolated from water sources in the Canary Islands, for the presence of human adenoviruses (HAdV) using a polymerase chain reaction (PCR)-based typing assay. A total of 34 of these strains were found to be positive for adenovirus belonging to four different HAdV serotypes (HAdV-1, 2, 8, and 37). We found that HAdV-2 was the most frequently encountered serotype amongst the Acanthamoeba strains, and their identification was confirmed by a nested PCR specific for this serotype. We showed that Acanthamoeba genotype T4 was highly associated with serotype HAdV-2, whereas Acanthamoeba genotype T3 was most often associated with adenovirus serotypes related to ocular diseases. Based on these data, we suggest that Acanthamoeba should be considered as a potential reservoir and perhaps even a transmitter of adenoviruses to human and other secondary hosts.

Detection of four adenovirus serotypes within water-isolated strains of Acanthamoeba in the Canary Islands, Spain. Publishing Authors By Initials

J Lorenzo-Morales,N Coronado-Alvarez,E ,SK Maciver,B Valladares,J Lorenzo-Morales,N Coronado-Alvarez,E ,SK Maciver,B Valladares,

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Detection of four adenovirus serotypes within water-isolated strains of Acanthamoeba in the Canary Islands, Spain. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: The American journal of tropical medicine and hygi

VOLUME: 77

Page Numbers: 753-6

Journal Abbreviation: Am. J. Trop. Med. Hyg.

ISSN: 0002-9637

DAY: 5

MONTH: Oct

YEAR: 2007

Detection of four adenovirus serotypes within water-isolated strains of Acanthamoeba in the Canary Islands, Spain. Information

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LANGUAGE: eng

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AFFILIATION: Instituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias, University of La Laguna, La Laguna, Canary Islands, Spain. jmlorenz@ull.es

Country: United States

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MEDLINETA: Am J Trop Med Hyg

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