Detection of epstein-barr virus in nasal T-cell lymphoma.

Detection of epstein-barr virus in nasal T-cell lymphoma. Research Abstract Details 

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Detection of epstein-barr virus in nasal T-cell lymphoma. Abstract Text:

Tomohiro Makoshi,Hiroomi Takahashi,Toru Kameya,Kazuo Yao,Yuichi Sato,Meijin Nakayama,Benio Tsuchiya,Makito Okamoto,

The close relationship between Epstein-Barr virus (EBV) and nasal T-cell lymphoma (NTL) has frequently been reported. However, the status of the infection, either lytic or latent, is obscure. This study involved 16 patients with NTL. Phenotypes of lymphoma cells were examined by immunohistochemical staining using CD3, CD4, CD8, CD20 and CD45RO monoclonal antibodies. EBV-encoded small nuclear RNA (EBER)-1 and EBV NotI tandem repeat region were detected by reverse transcription, using a rapid (< or = 60 min) in situ hybridization technique. Tumor cells expressed at least one T-cell marker, such as CD3, CD4, CD8 and CD45RO. CD20 was not detected in any of the cases. EBER-1 was identified in all cases; no Notl tandem DNA repeat was demonstrated. All cases demonstrated a T-cell phenotype. These data suggest that NTL is associated with EBV infection in the latent phase.

Detection of epstein-barr virus in nasal T-cell lymphoma. Publishing Authors By Initials

T Makoshi,H Takahashi,T Kameya,K Yao,Y Sato,M Nakayama,B Tsuchiya,M Okamoto,

For similar biochemical phenomena, metabolism, and nutrition: biochemical phenomena: molecular structure: base sequence: repetitive sequences, nucleic acid: tandem repeat sequences research abstracts see: biochemical phenomena, metabolism, and nutrition: biochemical phenomena: molecular structure: base sequence: repetitive sequences, nucleic acid: tandem repeat sequences research

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Detection of epstein-barr virus in nasal T-cell lymphoma. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Acta oto-laryngologica. Supplementum

VOLUME:

Page Numbers: 46-9

Journal Abbreviation:

ISSN: 0365-5237

DAY: 13

MONTH: 02

YEAR: 2002

Detection of epstein-barr virus in nasal T-cell lymphoma. Information

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LANGUAGE: eng

NlmUniqueID: 370355

Detection of epstein-barr virus in nasal T-cell lymphoma. Keywords Mesh Terms:

KEYWORDS: Tandem Repeat Sequences

MESH TERMS: genetics

Chemical & Substance for Abstract: Detection of epstein-barr virus in nasal T-cell lymphoma. Information

Substance Name: RNA, Viral

Registry Number: 0

Grant and Affiliation Information for Detection of epstein-barr virus in nasal T-cell lymphoma.

AFFILIATION:

Country: Norway

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MEDLINETA: Acta Otolaryngol Suppl

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